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1050 Venous Sinus Stenting for Idiopathic Intracranial Hypertension: A Large Single-Center Experience of Long-Term Efficacy and Safety
Abstract   Peer reviewed

1050 Venous Sinus Stenting for Idiopathic Intracranial Hypertension: A Large Single-Center Experience of Long-Term Efficacy and Safety

Elias Atallah, Basel Musmar, Antony Fuleihan, Joanna Roy, Kareem El-Naamani, Spyridon K. Karadimas, Sravanthi Koduri, Saman Sizdahkhani, Mario Zanaty, Stavropoula I. Tjoumakaris, …
Neurosurgery, Vol.72(Supplement_1), pp.189-189
04/2026
DOI: 10.1227/neu.0000000000003964_1050

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Abstract

INTRODUCTION: Idiopathic intracranial hypertension (IIH) presents with headaches, pulsatile tinnitus and papilledema. Venous sinus stenting (VSS) has demonstrated the ability to alleviate symptoms by reducing the pressure gradient. However, its efficacy as primary modality for IIH remains questionable. Our study reviews a single-center experience with VSS over three years. METHODS: This is a single center retrospective study of patients who underwent VSS for IIH between March 2021 to May 2024. All patients who failed medical management and presented with either a pre-operative pressure gradient ≥8 mm Hg or had clinical symptoms of IIH were included. Data was collected with regard to demographics, clinical presentation, procedural characteristics, post-operative complications and follow-up outcomes (complications, weight change, resolution of symptoms, emergency department (ED) visits and readmissions after discharge). RESULTS: 99 patients underwent 109 VSS procedures during the study period. 92.9% (n = 92) were female, and the mean age was 39.4 years (standard deviation [SD]: 11.8). 32.1% of patients (n = 35) had bilateral venous sinus stenosis and headaches were the most common presenting symptom (87.2%, n = 95). The average pressure gradient and procedure duration were 13.1 mmHg (SD: 11.4 mmHg) and 85.5 minutes (SD: 61.3 minutes). All patients demonstrated a reduction in pressure gradient immediately after VSS. Resolution of papilledema, headache, tinnitus and visual changes were noted in 62.1%, 45.3%, 54.1% and 68.1% patients, respectively. 19.3% of patients (n = 20) were readmitted, with an average time to readmission of 124.6 days (SD: 131.6) from the date of surgery. The average length of follow-up was 4.7 months. CONCLUSIONS: Our results demonstrates favorable short-term outcomes as evidenced by the resolution of pressure gradient and satisfactory long-term outcomes due to resolution of clinical symptoms of IIH. Future studies are necessary to draw conclusions about the optimal pressure gradient for VSS.

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