1631-P: From 1999 to 2022—Tracking Diabetes and Nonalcoholic Fatty Liver Disease (NAFLD) Mortality in the United States of America

SIDRAH Khan; Muhammad Usman Haider; HUSNAIN Ahmad; MIAN ZAHID JAN KAKAKHEL; ISHTIAQ Ahmad; UMAR Hayat; MUHAMMAD USMAN ARSHAD; MUHAMMAD F. Tahir

doi:10.2337/db25-1631-P

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1631-P: From 1999 to 2022—Tracking Diabetes and Nonalcoholic Fatty Liver Disease (NAFLD) Mortality in the United States of America

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1631-P: From 1999 to 2022—Tracking Diabetes and Nonalcoholic Fatty Liver Disease (NAFLD) Mortality in the United States of America

SIDRAH Khan, Muhammad Usman Haider, HUSNAIN Ahmad, MIAN ZAHID JAN KAKAKHEL, ISHTIAQ Ahmad, UMAR Hayat, MUHAMMAD USMAN ARSHAD and MUHAMMAD F. Tahir

Diabetes (New York, N.Y.), Vol.74(Supplement_1)

06/20/2025

DOI: 10.2337/db25-1631-P

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Abstract

Introduction and Objective: Almost 11.6% of the US adult population has Diabetes mellitus, which predisposes to obesity, ultimately leading to Non-alcoholic fatty liver disease (NAFLD). Methods: CDC WONDER was used to extract data for adults aged ≥ 25 years. Age- Adjusted Mortality Rates (AAMRs) per Million persons were calculated and trends were analyzed by calculating annual percent change (APC) and the average annual percent change (AAPC) using Joinpoint Version 5.2.0. Results: From 1999 to 2022, a total of 126,431 NAFLD and DM related deaths were recorded with most of the deaths occurring in Medical Facilities (43.5%) followed by Decedent’s homes (32.8%). The AAMR increased consistently from 1999 to 2016 (APC: 1.2, 95% CI: 0.3-1.9) and surged thereafter till 2022 (APC: 9.6; 95% CI: 7.2-14.6). During the COVID-19 pandemic, AAMR almost doubled. AAMR for males was greater than the females. American Indians and Hispanics displayed the highest AAMR, followed by NH Whites and other NH populations. AAMRs showed an increase over the years by census regions. Rural areas exhibited a higher AAMR (AAMR: 25.0, 95% CI: 24.6-25.3) than urban areas (AAMR: 21.2, 95% CI: 21.1-21.4). States with highest AAMR include Oklahoma and Texas while those with the lowest include Connecticut and New York. Conclusion: Increasing trends in NAFLD and DM- related deaths throughout the study period were seen, reaching a peak during the COVID- 19 pandemic between 2020-2022

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Title: Subtitle: 1631-P: From 1999 to 2022—Tracking Diabetes and Nonalcoholic Fatty Liver Disease (NAFLD) Mortality in the United States of America
Creators: SIDRAH Khan
Muhammad Usman Haider
HUSNAIN Ahmad
MIAN ZAHID JAN KAKAKHEL
ISHTIAQ Ahmad
UMAR Hayat
MUHAMMAD USMAN ARSHAD
MUHAMMAD F. Tahir
Resource Type: Abstract
Publication Details: Diabetes (New York, N.Y.), Vol.74(Supplement_1)
DOI: 10.2337/db25-1631-P
ISSN: 0012-1797
eISSN: 1939-327X
Publisher: AMER DIABETES ASSOC
Language: English
Date published: 06/20/2025
Academic Unit: Internal Medicine
Record Identifier: 9985088577902771

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