Abstract
1666. Sources and Preventability of Hospital-onset Bacteremia and Fungemia in the United States: Evaluation of a Potential Healthcare Quality Measure
Open forum infectious diseases, Vol.9(Supplement_2)
12/15/2022
DOI: 10.1093/ofid/ofac492.132
Abstract
Abstract Background Hospital-onset bacteremia and fungemia (HOB) is being proposed as a potential healthcare quality measure due to its clinical significance, objectivity, and ease of detection. However, information is lacking on sources of HOB and the proportion and types of cases considered preventable. Methods We evaluated sources and potential preventability of HOB cases at 12 hospitals using retrospective chart review. HOB was defined as a positive blood culture >= day 4 (admission date=day 1) for one or more organisms. Stratified sampling of cases by commensal and noncommensal organisms was used. Infectious disease physicians determined the source of HOB and rated preventability from 1-6 (1=definitely preventable to 6=definitely not preventable) using a previously validated guide. Ratings of 1–3 were collectively considered potentially preventable and 4–6 likely not preventable. Results We evaluated sources and potential preventability of HOB cases at 12 hospitals using retrospective chart review. HOB was defined as a positive blood culture >= day 4 (admission date=day 1) for one or more organisms. Stratified sampling of cases by commensal and noncommensal organisms was used. Infectious disease physicians determined the source of HOB and rated preventability from 1–6 (1=definitely preventable to 6=definitely not preventable) using a previously validated guide. Ratings of 1–3 were collectively considered potentially preventable and 4–6 likely not preventable. Conclusion Gastrointestinal and endovascular sources account for a large majority of noncommensal HOB cases. A high proportion of noncommensal HOB cases are likely not preventable. The presence of non-preventable events should be considered when using HOB as a quality measure. Approaches to identifying the subset of preventable noncommensal HOB events should be explored. Disclosures Scott Fridkin, MD, Pfizer: Grant/Research Support Andi L. Shane, MD, MPH, MSc, International Scientific Association for Probiotics and Prebiotics (ISAPP): travel and lodging to attend international meeting to deliver a presentation, June 2022 Aaron Milstone, MD, Merck: Grant/Research Support Rajeshwari Nair, MBBS, PhD, Vertex Pharmaceuticals: Salary.
Details
- Title: Subtitle
- 1666. Sources and Preventability of Hospital-onset Bacteremia and Fungemia in the United States: Evaluation of a Potential Healthcare Quality Measure
- Creators
- Surbhi Leekha - University of Maryland, BaltimoreGwen Robinson - University of Maryland, BaltimoreJesse T Jacob - Emory UniversityScott Fridkin - Emory UniversityAndi L Shane - Children's Healthcare of AtlantaAnna Sick-Samuels - Johns Hopkins UniversityAaron Milstone - Johns Hopkins UniversityRajeshwari Nair - University of IowaEli N Perencevich - University of IowaMireia Puig-Asensio - University of IowaTakaaki Kobayashi - University of IowaJeanmarie Mayer - University of UtahJulia Lewis - Lake City VA Medical CenterSusan C Bleasdale - University of Illinois ChicagoEric Wenzler - Indo-American CenterAlfredo J Mena LoraJonathan Baghdadi - University of Maryland, BaltimoreGregory M Schrank - University of Maryland, BaltimoreGita Nadimpalli - University of Maryland, BaltimoreAnthony Harris - University of Maryland, Baltimore
- Resource Type
- Abstract
- Publication Details
- Open forum infectious diseases, Vol.9(Supplement_2)
- DOI
- 10.1093/ofid/ofac492.132
- ISSN
- 2328-8957
- eISSN
- 2328-8957
- Language
- English
- Date published
- 12/15/2022
- Academic Unit
- Infectious Diseases; Epidemiology; General Internal Medicine; Internal Medicine
- Record Identifier
- 9984339543302771
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