Abstract
329 - Exploring Gender Differences in the Link Between Chronic Overlapping Pain Conditions and Post-Acute COVID-19 Sequelae
The journal of pain, Vol.29(Supplement), 105127
04/2025
DOI: 10.1016/j.jpain.2025.105127
Abstract
Chronic overlapping pain conditions (COPCs) are medically complex, intersecting conditions. The emergence of post-acute sequelae of COVID-19 (PASC), for which pain is a common symptom, has further complicated the chronic pain landscape. While women are more likely to have both COPCs and PASC, the role of gender identity in the association between COPCs and PASC remains unclear. This study assessed the impact of gender identity on a) prior COPCs and the odds of PASC and b) prior PASC and the odds of a COPC. Adults in the United States (N=2808) participated in an online survey. The average age was 41.5 years (SD=18.5), and most identified as women (52.9%), white (88.6%), and non-Hispanic/Latine (87.4%). Participants were asked to report the presence of seven COPCs both prior to and after COVID-19 infection. PASC status was also reported. Multivariate logistic regression models were utilized. Gender identity was included in interaction terms, and analyses were stratified to explore the role of gender identity in these relationships. Having a prior COPC was associated with significantly greater odds of PASC development, with a stronger association in men (aOR=3.87; 95% CI=2.75-5.43) than women (aOR=1.82; 95% CI=1.34-2.46). Having PASC was associated with similarly greater odds of subsequent COPC development among both men (aOR=7.42; 95% CI=5.01-11.00) and women (aOR=7.39; 95% CI=5.00-10.92). Considering prior COPCs may be helpful in assessing an individual’s risk for PASC following COVID-19, particularly among men.
Details
- Title: Subtitle
- 329 - Exploring Gender Differences in the Link Between Chronic Overlapping Pain Conditions and Post-Acute COVID-19 Sequelae
- Creators
- Zoe SirotiakEmily B.K. ThomasJenna L. AdamowiczMarian L. Kohut
- Resource Type
- Abstract
- Publication Details
- The journal of pain, Vol.29(Supplement), 105127
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.jpain.2025.105127
- ISSN
- 1526-5900
- eISSN
- 1528-8447
- Language
- English
- Date published
- 04/2025
- Academic Unit
- Psychological and Brain Sciences
- Record Identifier
- 9984821344602771
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