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566 THE PREVALENCE OF CYTOMEGALOVIRUS INFECTION IN MIDWEST DAY CAKE CENTER
Abstract   Open access   Peer reviewed

566 THE PREVALENCE OF CYTOMEGALOVIRUS INFECTION IN MIDWEST DAY CAKE CENTER

Jody R Murph, James F Bale, Stanley Perlman, Norman S Swack and Fred G Smith
Pediatric research, Vol.19(4), pp.205-205A
04/1985
DOI: 10.1203/00006450-198504000-00596
url
https://doi.org/10.1203/00006450-198504000-00596View
Published (Version of record) Open Access

Abstract

Recent studies indicate that children in day care centers (DCC) have a frequency of CMV infection that exceeds 50%. Such CMV-infected children may pose a threat to the nonimmune day care worker of childbearing age. To determine whether CMV infection was highly prevalent in a DCC in a different geographic location than previously reported, we assessed CMV excretion in 40 children from middle and upper middle class homes attending a large raidwestern DCC. The children were 88% Caucasian and ranged in age from 4 to 66 rao. Urine and/or saliva samples were obtained for CMV culture from 39 children. Four of 39 children (10%) had CMV present in saliva. Seven of 24 children (29%) had CMV in their urine. CMV viruria was found in 4 of 8 children (50%) ≤ 24 mo. old; 1 of 6 children (16%) 25 to 36 mo. of age; and 2 of 10 children (20%) > 36 mo. None of the 7 day care workers had CMV in urine or saliva. Of 5 workers in whom serum was obtained only 1 (20%) had CMV antibody detected by complement fixation. These results indicate that the prevalence of CMV infection in this DCC may be lower than the prevalence rate previously reported. Nonetheless, this study supports the observation that CMV infection frequently occurs in children attending DCC and indicates that certain epidemiologic factors, such as age of the children and geographic location of the center may affect the frequency of CMV infection.

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