Abstract
Absence of vaginal methicillin-resistant staphylococcus aureus (MRSA) carriage in the setting of increasing community-associated MRSA rates
American journal of obstetrics and gynecology, Vol.195(6 Supplement), pp.S70-S70
12/2006
DOI: 10.1016/j.ajog.2006.10.219
Abstract
Objective
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has emerged as a major public health problem nationwide, and outbreaks have occurred among postpartum women and neonates. In Iowa, we have also observed increased CA-MRSA incidence, including outbreaks in healthcare facilities. To determine the risk of CA-MRSA emergence among postpartum women and neonates, we sought to determine MRSA vaginal carriage rates among pregnant women at the time of routine Group B streptococcus (GBS) screening.
Study design
We performed prospective surveillance for MRSA carriage among all pregnant women from whom rectovaginal GBS screening cultures were obtained from March 2006 to July 2006. All cultures were processed using standard methods for detection of GBS, and in addition a CHROMagar MRSA medium plate (BD diagnostics, Sparks, MD) was added for detection of MRSA. In addition, since 1999 invasive MRSA infection has been a reportable disease in Iowa, and all MRSA isolates obtained from statewide surveillance have been submitted to the University of Iowa for further characterization, including pulsed field gel electrophoresis, SCCmec typing, and detection of Panton Valentine Leukocidin (PVL) gene.
Results
Of 535 cultures obtained, GBS was isolated from 105 (28%). MRSA was not isolated from any vaginal cultures obtained (0%; 95% confidence interval: 0-0.6%). Meanwhile, prospective statewide reporting revealed an increased incidence of infection with CA-MRSA genotype (USA300, SCCmec IV, PVL positive) beginning in 2004.
Conclusion
Our prospective surveillance revealed no evidence of vaginal MRSA carriage among pregnant women in the setting of increased statewide CA-MRSA incidence. Further study of the epidemiology of CA-MRSA in pregnant women and neonates is needed before routine screening of vaginal cultures for MRSA can be recommended.
Details
- Title: Subtitle
- Absence of vaginal methicillin-resistant staphylococcus aureus (MRSA) carriage in the setting of increasing community-associated MRSA rates
- Creators
- Debra Piehl - University of IowaDaniel Diekema - University of IowaWanita Howard - University of IowaJanet Andrews - University of Iowa
- Resource Type
- Abstract
- Publication Details
- American journal of obstetrics and gynecology, Vol.195(6 Supplement), pp.S70-S70
- Publisher
- Mosby, Inc
- DOI
- 10.1016/j.ajog.2006.10.219
- ISSN
- 0002-9378
- eISSN
- 1097-6868
- Language
- English
- Date published
- 12/2006
- Academic Unit
- Obstetrics and Gynecology; Infectious Diseases; Internal Medicine
- Record Identifier
- 9984697133102771
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