Abstract 13672: Quality of Life Impact of Transcatheter Edge to Edge Repair of Mitral Valve With the Mitraclip System in Patients With Mitral Regurgitation and Cardiogenic Shock

Mina M Kerolos; Caleb Chiang; Joseph Eid; Ethan Ritz; Laith A Derbas; tisha M suboc; Fareed M Collado; Clifford J Kavinsky; Hussam Suradi

doi:10.1161/circ.146.suppl_1.13672

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Abstract 13672: Quality of Life Impact of Transcatheter Edge to Edge Repair of Mitral Valve With the Mitraclip System in Patients With Mitral Regurgitation and Cardiogenic Shock

Mina M Kerolos, Caleb Chiang, Joseph Eid, Ethan Ritz, Laith A Derbas, tisha M suboc, Fareed M Collado, Clifford J Kavinsky and Hussam Suradi

Circulation (New York, N.Y.), Vol.146(Suppl_1), pp.A13672-A13672

11/08/2022

DOI: 10.1161/circ.146.suppl_1.13672

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Abstract

Introduction: Transcatheter Edge to Edge Repair (TEER) of the mitral valve is a viable option for patients with moderate to severe mitral regurgitation (MR) who are at high surgical risk. TEER has been shown to improve quality of life (QOL) in patients with MR. Data is limited regarding QOL in patients with MR and cardiogenic shock (CS) who undergo TEER. Methods: A single-center, retrospective cohort study including adult patients with moderate to severe MR and CS who underwent TEER between January 2012 and December 2021. CS was defined as a sustained systolic blood pressure <90mmHg for at least 1 hour, use of inotropes, vasopressors, or mechanical circulatory support, and clinical and lab findings of end-organ damage. The primary outcome was change in disease-specific health status (Kansas City Cardiomyopathy Questionnaire-Overall Summary score [KCCQ-OS] at 30 days. Statistical analysis was done using Wilcoxon signed-rank test and t-test. Results: Thirty-three patients with mod-severe MR and CS had undergone TEER (See table 1 for baseline characteristics) . KCCQ data were available on 30% survivors at 30 days. KCCQ increased from 17.19 (11.88) before TEER to 53.85 (30.89) in 30 days (mean change 36.67; 95% CI 14.24-59.09; P<0.05, see table2). There was an improvement in 2 out of 4 KCCQ domains; symptoms frequency (mean change 49.17; 95% CI 18.17-80.16; P<0.05) and social limitation (mean change 49.54; 95% CI 22.25-76.83); P<0.05). Conclusion: TEER of the mitral valve improves QOL at 30 days in patients with moderate to severe MR and CS.

Quality of Life

Shock, cardiogenic

Mitral regurgitation

Mitral valve disease

Details

Title: Subtitle: Abstract 13672: Quality of Life Impact of Transcatheter Edge to Edge Repair of Mitral Valve With the Mitraclip System in Patients With Mitral Regurgitation and Cardiogenic Shock
Creators: Mina M Kerolos - Rush University
Caleb Chiang - Rush University
Joseph Eid - Rush University
Ethan Ritz - Rush University
Laith A Derbas - Rush University
tisha M suboc - Rush University
Fareed M Collado - Rush University
Clifford J Kavinsky - Rush University
Hussam Suradi - Rush University
Resource Type: Abstract
Publication Details: Circulation (New York, N.Y.), Vol.146(Suppl_1), pp.A13672-A13672
DOI: 10.1161/circ.146.suppl_1.13672
ISSN: 0009-7322
eISSN: 1524-4539
Publisher: Lippincott Williams & Wilkins
Language: English
Date published: 11/08/2022
Academic Unit: Internal Medicine
Record Identifier: 9985218630302771

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