Abstract
Abstract 14159: Characteristics and Outcomes in COVID-19 Pediatric In-Hospital Cardiac Arrest Patients
Circulation (New York, N.Y.), Vol.144(Suppl_2), p.A14159
11/16/2021
DOI: 10.1161/circ.144.suppl_2.14159
Abstract
Introduction:
Survival of adult patients with COVID-19 who had an in-hospital cardiac arrest (IHCA) are poor. Characteristics and outcomes for pediatric IHCA patients with COVID-19 are unknown.
Hypothesis:
We hypothesized that pediatric COVID-19 patients would have worse survival outcomes when compared to non-COVID patients.
Methods:
A multicenter, multinational cohort of pediatric IHCA in the pediRES-Q collaborative were reviewed (March 1, 2020 - April 1, 2021). We characterized patients with COVID-19 compared to patients without COVID-19 and investigated whether COVID-19 was associated with survival outcomes using multivariate logistic regression with mixed effects.
Results:
We identified 362 pediatric IHCAs of which 14 were COVID-19 positive. For non-COVID-19 vs COVID-19 patients respectively, median [Q1; Q3] age was 1.0 [0.3; 7.1] vs. 7.1 [1.5; 14.0] years and 42% vs. 43% were female. Immediate cause of arrest was hypotension: 8% vs. 43%, respiratory decompensation: 19% vs. 21%, and hypoxia 22% vs. 36% for non-COVID-19 vs. COVID-19 patients. For non-COVID-19 vs COVID-19 patients, total CPR duration was 10 [4; 33] min vs 19 [5; 33] min (for non-return of spontaneous circulation (ROSC) cases only: 35 [20; 55] min vs 34 [24; 34] min). For non-COVID-19 vs COVID-19 patients, ROSC was 79% vs. 57%, aOR: 0.48 (95% CI: 0.24-0.98), survival to hospital discharge was 45% vs. 29%, aOR: 0.63 (95% CI: 0.25-1.57) and survival with favorable neurological outcome was 39% vs. 21%, aOR: 0.51 (95% CI: 0.16-1.65).
Conclusions:
In a pediatric resuscitation quality improvement collaborative, pediatric IHCA patients with COVID-19 were older when compared to non-COVID-19 patients. Median CPR duration was >30 minutes for COVID-19 non-survivors, COVID-19 patients had lower chance of ROSC when compared to non-COVID-19 patients but considerably better survival outcomes than those reported for adults.
Details
- Title: Subtitle
- Abstract 14159: Characteristics and Outcomes in COVID-19 Pediatric In-Hospital Cardiac Arrest Patients
- Creators
- Kasper G Lauridsen - Randers Regional Hosp, Randers, DenmarkTodd Sweberg - CCMC, New Hyde Park, NYSarah E Haskell - University of IowaOrsola Gawronski - Rome, Italy, ItalyDana E Niles - CHILDRENS HOSP PHILADELPHIA, Philadelphia, PAMaya Dewan - Cincinnati Children's Hospital Medical CenterSophie Skellett - Great Ormond Street HospitalJordan M Duval-arnould - Johns Hopkins UniversityGabriella BottariVinay M Nadkarni - 1957, Philadelphia, PAAnita Sen - New York, NY
- Resource Type
- Abstract
- Publication Details
- Circulation (New York, N.Y.), Vol.144(Suppl_2), p.A14159
- DOI
- 10.1161/circ.144.suppl_2.14159
- ISSN
- 0009-7322
- eISSN
- 1524-4539
- Language
- English
- Date published
- 11/16/2021
- Academic Unit
- Critical Care; Stead Family Department of Pediatrics
- Record Identifier
- 9984354404002771
Metrics
12 Record Views