Abstract 14296: Agatston Aortic Valve Calcium Score and the Prediction of Transcatheter Aortic Valve Replacement Complications: A Systematic Review and Meta-Analysis

Yehia Saleh; Abdullah Al-abcha; Nadeen N Faza; Stephen H Little; Su Min Chang

doi:10.1161/circ.144.suppl_1.14296

Abstract 14296: Agatston Aortic Valve Calcium Score and the Prediction of Transcatheter Aortic Valve Replacement Complications: A Systematic Review and Meta-Analysis

Yehia Saleh, Abdullah Al-abcha, Nadeen N Faza, Stephen H Little Su Min Chang

Circulation (New York, N.Y.), Vol.144(Suppl_1), pp.A14296-A14296

11/16/2021

: 10.1161/circ.144.suppl_1.14296

IntroductionAortic valve calcium score (AVCS) is used to determine aortic stenosis severity, but whether it affects transcatheter aortic valve replacement (TAVR) complications is not well studied. MethodsWe conducted a literature search in PubMed using the key words “Aortic valve”, “Calcium score”, “Aortic stenosis”, “Computed tomography”,” Calcification”, “Calcium”, “TAVR”, “TAVI”, “Outcomes”, “Complications” up to December, 31st, 2020. Several studies assessed the different factors affecting TAVR outcomes, of these, AVCS was usually found to be one of them. Only a few studies investigated the effect of AVCS on TAVR outcomes. We included studies classifying their patient cohort into high and low AVCS. These studies used the Agatston AVCS derived from non-contrast computed tomography (CT) in patients with native aortic valves and they investigated the TAVR outcomes in both groups. ResultsThree studies were included in our meta-analysis with a total number of 1839 patients. Our pooled analysis showed a similar risk of 30-day mortality (low AVCS 2% vs high AVCS 2.5%, P=0.63), Permanent pacemaker implantation (low AVCS 13.3 % vs high AVCS 11.9 %, P=0.73), Stroke (low AVCS 2.54% vs high AVCS 2.3%, P=0.69), and Major vascular complications (low AVCS 7.3% vs high AVCS 5.5%, P=0.60). ConclusionThe severity of Aortic valve calcification calculated by the Agatston AVCS had no impact on 30-day mortality, stroke, major vascular complications, or the need for a permanent pacemaker after TAVR is performed.

: Abstract 14296: Agatston Aortic Valve Calcium Score and the Prediction of Transcatheter Aortic Valve Replacement Complications: A Systematic Review and Meta-Analysis
: Yehia Saleh - Houston Methodist
Abdullah Al-abcha - Michigan State University
Nadeen N Faza - NADEEN FAZA, Houston, TX
Stephen H Little - Houston Methodist
Su Min Chang - Methodist Hospital
: Abstract
: Circulation (New York, N.Y.), Vol.144(Suppl_1), pp.A14296-A14296
: Lippincott Williams & Wilkins
: 10.1161/circ.144.suppl_1.14296
: 0009-7322
: 1524-4539
: English
: 11/16/2021
: Internal Medicine
: 9984757159402771