Abstract
Abstract 16783: Diagnostic Accuracy of Coronary Computed Tomography Angiography in Patients Undergoing Cardiac Valve Surgery: Systematic Review and Meta-analysis
Circulation (New York, N.Y.), Vol.134(Suppl_1 Suppl 1), pp.A16783-A16783
11/11/2016
Abstract
IntroductionThe objective of this study is to investigate the diagnostic accuracy of coronary computed tomography angiography (CCTA) in patients undergoing cardiac valve surgery using invasive coronary angiography (ICA) as gold standard.HypothesisCCTA is accurate for identification of significant coronary stenosis in cardiac valve surgery patientsMethodsWe search databases for all diagnostic studies of CCTA in patients undergoing cardiac valve surgery which reported diagnostic testing characteristics required to pool summary sensitivity, specificity, positive likelihood ratio and negative likelihood ratio. Significant stenosis in both CCTA and ICA is defined by >50% stenosis in any coronary artery, in-stent stenosis or bypass graft.ResultsNine studies evaluated 659 patients (mean age = 66 years, 52% men). The pooled prevalence of significant stenosis determined by ICA is 25% (range 18%-56%). Summary receiver operating characteristic (sROC) analysis demonstrates a summary area under curve (sAUC) of 0.97. The pooled sensitivity and negative likelihood ratio of CCTA in identifying significant stenosis determined by ICA are 96% and 0.07 without significant inter-study heterogeneity. The pooled specificity and positive likelihood ratio are 89% and 7.36 with mild-moderate inter-study heterogeneity.ConclusionsIn patients undergoing cardiac valve surgery, CCTA has excellent sensitivity and negative likelihood ratio to exclude significant coronary stenosis. Our meta-analysis supports the role of preoperative computed tomography as a rule-out test in this population.
Details
- Title: Subtitle
- Abstract 16783: Diagnostic Accuracy of Coronary Computed Tomography Angiography in Patients Undergoing Cardiac Valve Surgery: Systematic Review and Meta-analysis
- Creators
- Kongkiat Chaikriangkrai - University of IowaGhanshyam Palamaner Subash ShantaAref Bin AbdulhakHye JhunJay BhamaGardar Sigurdsson
- Resource Type
- Abstract
- Publication Details
- Circulation (New York, N.Y.), Vol.134(Suppl_1 Suppl 1), pp.A16783-A16783
- Publisher
- by the American College of Cardiology Foundation and the American Heart Association, Inc
- ISSN
- 0009-7322
- eISSN
- 1524-4539
- Language
- English
- Date published
- 11/11/2016
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984361570002771
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