Abstract 263: Broadway 8 system: A Multicenter Early Evaluation of Safety, Performance, and Clinical Outcomes in Mechanical Thrombectomy

R Ezzeldin; O Mir; A Delora; S Boo; S Ortega-Gutierrez; J. N Dolia; D. C Haussen; C Schirmer; F Al-Saeigh; J Mascitelli; A. E Hassan; M Khan; J Burkhardt; O Malik; D Diehl; M Zanaty; A Aljuboori; S Miller; V Srinivasan; K Scott; Z Ali; M Ezzeldin

doi:10.1161/svi270000_263

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Abstract 263: Broadway 8 system: A Multicenter Early Evaluation of Safety, Performance, and Clinical Outcomes in Mechanical Thrombectomy

R Ezzeldin, O Mir, A Delora, S Boo, S Ortega-Gutierrez, J. N Dolia, D. C Haussen, C Schirmer, F Al-Saeigh, J Mascitelli, …

Stroke: vascular and interventional neurology, Vol.5(S1)

11/01/2025

DOI: 10.1161/svi270000_263

PMCID: PMC12849954

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Abstract

Background Large‐bore aspiration catheters are integral to mechanical thrombectomy (MT) for large vessel occlusions (LVOs), offering potential for improved first pass success and faster recanalization. Objective Assess the clinical performance, efficacy, and safety profile of the Broadway 8 system as a primary aspiration device in MT of LVOs. Methods A multicenter observational study across 8 U.S. comprehensive stroke centers. Efficacy outcomes included first pass effect (FPE), defined as a single‐pass modified Treatment in Cerebral Infarction (mTICI) score ≥2c, and successful reperfusion (final mTICI ≥2b). Safety outcomes included device‐related complications, symptomatic intracranial hemorrhage (sICH), and inpatient mortality. Functional outcomes included modified Rankin Scale (mRS) at discharge and delta National Institutes of Health Stroke Scale (NIHSS) score. Logistic regression was used to assess predictors of thrombus access and intermediate catheter use. Results 49 patients were included. Broadway 8 system reached the thrombus in 44 (89.8%). Median puncture‐to‐thrombus and puncture‐to‐reperfusion times were 11 min (IQR 9‐18) and 20 min (14‐31). FPE was achieved in 20 (40.8%). Successful reperfusion was achieved in 46/49 (93.8%), with 35 (71.4%) using Broadway 8. sICH occurred in 2 patients (4.1%). Median mRS at discharge was 3.0 (IQR 1.0‐4.0); delta NIHSS was 8 (IQR 5‐12). Regression analysis showed faster reperfusion when Broadway 8 was used without an intermediate catheter. Conclusion The Broadway 8 system appears to be a safe and effective frontline aspiration device, demonstrating a safety and efficacy profile comparable to other large‐bore aspiration systems that incorporate delivery‐assist technology.

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Title: Subtitle: Abstract 263: Broadway 8 system: A Multicenter Early Evaluation of Safety, Performance, and Clinical Outcomes in Mechanical Thrombectomy
Creators: R Ezzeldin - University of Central Florida
O Mir
A Delora
S Boo
S Ortega-Gutierrez
J. N Dolia
D. C Haussen - Emory University
C Schirmer - Geisinger Health System
F Al-Saeigh
J Mascitelli - The University of Texas at San Antonio Health Science Center
A. E Hassan - Valley Baptist Medical Center
M Khan - Valley Baptist Medical Center
J Burkhardt
O Malik
D Diehl
M Zanaty - University of Iowa
A Aljuboori
S Miller
V Srinivasan - University of Pennsylvania
K Scott
Z Ali
M Ezzeldin
Resource Type: Abstract
Publication Details: Stroke: vascular and interventional neurology, Vol.5(S1)
DOI: 10.1161/svi270000_263
PMCID: PMC12849954
ISSN: 2694-5746
eISSN: 2694-5746
Publisher: Wiley Subscription Services, Inc
Language: English
Date published: 11/01/2025
Academic Unit: Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9985089030502771

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