Abstract
Abstract 8423: Prevalence and Outcomes of Intermediate Saphenous Vein Graft Lesions: Findings from the Stenting of Saphenous Vein Grafts Randomized-Controlled Trial
Circulation (New York, N.Y.), Vol.124(suppl_21)
11/22/2011
DOI: 10.1161/circ.124.suppl_21.A8423
Abstract
Abstract only Background: We sought to examine the prevalence and progression rate of intermediate SVG lesions in the Stenting Of Saphenous vein grafts (SOS) trial. Methods: The baseline and follow-up angiograms of the 80 patients participating in the SOS trial were analyzed to determine the prevalence of intermediate (30-60% angiographic diameter stenosis) SVG lesions and their progression rate. Results: At least one intermediate SVG lesion was present in 31 of 143 (22%) SVGs in 27 of 80 (34%) patients. Patients with intermediate SVG lesions were older and more likely to present with myocardial infarction. Most intermediate lesions were present in the vein grafts the required stents (20 grafts in 19 patients). During a median follow-up of 35 months, angiographic follow-up was available for 28 grafts in 25 patients. Progression (defined as percent diameter stenosis ≥70% but <100% at follow-up angiography) was seen in 11 of 28 SVGs (39%) in 11 of 25 patients (44%). The rate of progression of the intermediate lesion at 12, 24 and 36 months was 28% and 47% and 84%, respectively (Figure). Seven of 11 patients (64%) whose intermediate SVG lesion progressed presented with an acute coronary syndrome, and 8 (73%) underwent a percutaneous coronary intervention. Four of the 28 grafts with intermediate lesions at baseline were occluded at follow-up; all of those SVGs had received a stent as part of the SOS trial. Conclusions: Among patients undergoing SVG lesion stenting, intermediate SVG lesions are common, have high rates of progression, and frequently present as an acute coronary syndrome.
Details
- Title: Subtitle
- Abstract 8423: Prevalence and Outcomes of Intermediate Saphenous Vein Graft Lesions: Findings from the Stenting of Saphenous Vein Grafts Randomized-Controlled Trial
- Creators
- Abdul-rahman R Abdel-karim - Cardiology Dept, VA North Texas Healthcare System and Univ of Texas Southwestern Med Cntr at Dallas, Dallas, TXMonica da Silva - VA North Texas Health Care SystemChristopher Lichtenwalter - VA North Texas Health Care SystemJames A de Lemos - VA North Texas Health Care SystemOwen Obel - VA North Texas Health Care SystemTayo Addo - VA North Texas Health Care SystemMichele Roesle - VA North Texas Health Care SystemDonald Haagen - VA North Texas Health Care SystemBavana V Rangan - VA North Texas Health Care SystemLorenza Makke - VA North Texas Health Care SystemOmar M Jeroudi - VA North Texas Health Care SystemDeepa Raghunathan - VA North Texas Health Care SystemBilal Saeed - University of ToledoJoseph K Bissett - Central Arkansas Veterans Healthcare SystemRajesh Sachdeva - Central Arkansas Veterans Healthcare SystemVassilios V Voudris - Cardiology Dept, Onassis Cardiac Surgery Cntr, Athens, Greece, Athens, GreecePanagiotis Karyofillis - Onassis Cardiac Surgery CenterBiswajit Kar - Michael E. DeBakey VA Medical CenterJames Rossen - Cardiology Dept, Iowa City Veteran Affairs Med Cntr, Iowa City, Iowa, Iowa City, IAPanayotis Fasseas - Medical College of WisconsinPeter Berger - Geisinger Medical CenterSubhash Banerjee - VA North Texas Health Care SystemEmmanouil S Brilakis - VA North Texas Health Care System
- Resource Type
- Abstract
- Publication Details
- Circulation (New York, N.Y.), Vol.124(suppl_21)
- DOI
- 10.1161/circ.124.suppl_21.A8423
- ISSN
- 0009-7322
- eISSN
- 1524-4539
- Language
- English
- Date published
- 11/22/2011
- Academic Unit
- Neurosurgery; Cardiovascular Medicine; Internal Medicine; Neurology
- Record Identifier
- 9984697056502771
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