Abstract
Abstract P79: Decline in Mild Stroke Presentations and Intravenous Thrombolysis During the Covid-19 Pandemic: The Society of Vascular and Interventional Neurology Registry
Stroke (1970), Vol.52(Suppl_1), p.AP79
03/2021
DOI: 10.1161/str.52.suppl_1.P79
Abstract
Introduction:
To evaluate overall ischemic stroke rates, specific subtypes, and clinical presentation during the COVID-19 pandemic in a multicenter observational study from eight states across US.
Methods:
We compared all ischemic strokes admitted between January 2019 and May 2020, grouped as; March-May 2020 (COVID-19 period), March-May 2019 (seasonal pre-COVID period) and November 2019-January 2020 (immediate pre-COVID-19 period). Primary outcome was stroke severity at admission measured by NIHSS stratified as mild (0-7), moderate (8-14), and severe (>14) symptoms. Secondary outcomes were number of large vessel occlusions (LVOs), stroke etiology, IV-tPA rates, and disposition.
Results:
Of the 7,969 patients diagnosed with acute stroke during the study period, 933 (12%) presented in the COVID-19 period, 1319 (17%), and 1254 (16%) presented in the seasonal pre-COVID-19 and immediate pre-COVID-19 periods, respectively. Significant decline was observed in the weekly mean volume of newly diagnosed strokes (98±7.3 vs 50±20, p<0.01 and 95±10.5 vs 50±20, p<0.01), LVOs (16.5±3.8 vs 8.3±5.9, p<0.01 and 14.3± 4.5 vs 8.3±5.9, p<0.01), and IV-tPA (5.3±2.9 vs 10.9±3.4 and 12.7±4.1, p<0.01). Mean weekly proportion of LVOs remained the same, when compared with seasonal pre-COVID-19 period (18%±5 vs 16%±7, p=0.24) and immediate pre-COVID-19 period (17.4%±4 vs. 16%±7, p=0.32). Additionally, these patients presented with less severe disease (NIHSS<14; aOR: 0.63, 95%CI: 0.41-0.97, p=0.035) during the COVID-19 period as compared to immediate pre-COVID-19 period.
Conclusions:
We observed a decrease in newly diagnosed stroke cases and rates of IV-tPA administration, while the LVO frequency remained unchanged during the COVID-19 pandemic. Additionally, these stroke patients had more severe presentations.
Details
- Title: Subtitle
- Abstract P79: Decline in Mild Stroke Presentations and Intravenous Thrombolysis During the Covid-19 Pandemic: The Society of Vascular and Interventional Neurology Registry
- Creators
- Mudassir Farooqui - University of IowaSantiago Ortega-Gutierrez - University of IowaAlicia Zha - UT Health Science Cntr Houston, Houston, TXAlexandra L Czap - University of Texas at Houston, Houston, TXSebaugh Jacob - The University of Texas Health Science Center at HoustonShashvat Desai - Dignity HealthAshutosh Jadhav - University of PittsburghNirav VoraVivek Rai - Riverside Methodist HospitalTudor G Jovin - Cooper Neurological Institute, Camden, NJJesse Thon - Camden, NJMark HeslinLauren ThauCynthia Zevallos - University of IowaDarko Quispe-Orozco - University of IowaDinesh Jillella - Emory UniversityFadi B Nahab - Emory UniversityMahmoud MohammadenRaul G Nogueira - Emory UniversityDiogo C Haussen - Emory UniversityThanh Nguyen - Boston, MAJose Romero - Neurology, Boston Med Cntr, Boston, MAHugo Aparicio - Neurology, Boston Med Cntr, Boston, MAMohamed Osman - ToledoIsrar Haq - Mercy HealthDavid S Liebeskind - University of California, Los AngelesAmeer E Hassan - Valley Baptist Medical CenterOsama O Zaidat - Mercy St. Vincent Medical CenterJames E Siegler - James E Siegler, Philadelphia, PA
- Resource Type
- Abstract
- Publication Details
- Stroke (1970), Vol.52(Suppl_1), p.AP79
- DOI
- 10.1161/str.52.suppl_1.P79
- ISSN
- 0039-2499
- eISSN
- 1524-4628
- Language
- English
- Date published
- 03/2021
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984303438502771
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