Abstract
Age-related differences in anterior cingulate-insula connectivity are associated with the fronto-executive but not emotional saliency network
Journal of Cognitive Neuroscience. Supplement, Vol.2013, pp.154b-154b
01/01/2013
Abstract
Research has shown that healthy aging is accompanied by declines in executive functioning, but enhanced emotion processing and regulation. The neural architecture hypothesized to underlie these processes has a high degree of shared regions. Studies of intrinsic connectivity networks, which look at temporally correlated patterns of activity across separate brain regions, may provide insight as to how aging is associated with differential changes in brain networks involved in executive function and emotional processing. The present study examined resting state functional MRI data from a group of 60 healthy adults between the ages of 19 and 83. We used a region of interest (ROI) approach to look at networks related to executive function and emotional processes, the fronto-executive network and the emotional saliency network, respectively. Because these networks share ROIs in the dorsal anterior cingulate (dACC) and the left and right insular cortex, we further examined age-related differences in network correlation strength between subsets of these networks that do not contain the overlapping regions. Age was associated with less connectivity strength in the fronto-executive network only when the dACC and insular cortex regions were included. Age was not associated with the functional integration of the dACC and insula with the salience network. Thus fronto-executive network changes appear to be driven by selectively lower connectivity between the dACC and insular cortices within the fronto-executive network in older adults. Preserved connectivity of the salience network in aging adults may reflect older adults' greater focus on emotion regulation and attending to positive affective information.
Details
- Title: Subtitle
- Age-related differences in anterior cingulate-insula connectivity are associated with the fronto-executive but not emotional saliency network
- Creators
- Matthew SuttererMichelle VossMerry ManiChelsea WongGillian CookeAmy BelfiTimothy WengDaniel TranelEdward McAuleyArthur Kramer
- Resource Type
- Abstract
- Publication Details
- Journal of Cognitive Neuroscience. Supplement, Vol.2013, pp.154b-154b
- ISSN
- 1096-8857
- Language
- English
- Date published
- 01/01/2013
- Academic Unit
- Psychological and Brain Sciences; Radiology; Neurology; Iowa Neuroscience Institute
- Record Identifier
- 9984071709402771
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