Abstract
Associations Between 24-hour Activity And Glycemic Response During The Second Trimester Of Pregnancy: 2547
Medicine and science in sports and exercise, Vol.57(10S), pp.816-817
10/2025
DOI: 10.1249/01.mss.0001161960.67420.ef
Abstract
PURPOSE: This study examined associations between a 24-hour activity composition (sleep, sedentary [SED], light physical activity [LPA], and moderate-to-vigorous physical activity [MVPA]) and 1-hour 50-gram oral glucose screening test in pregnant women.
METHODS: This cross-sectional analysis is part of the Pregnancy 24/7 cohort, conducted across three US university sites (Iowa, Pittsburgh, and West Virginia). Data from the second trimester were collected from 384 women (mean age 30.7 ± 4.3 years) using activPAL3 micro and Actiwatch Spectrum Plus devices, worn for 7 consecutive days to capture the 24-hour activity cycle. Glucose screening data were obtained from medical records. Multivariable linear regression models were applied using a compositional data analysis approach, adjusted for age, pre-pregnancy BMI, race and ethnicity, and study site.
RESULTS: On average, participants had a glucose result of 119.6 ± 28.0 mg/dL, and the 24-hour activity compositional means were: sleep (519.3 min [36%]), SED (612.6 min [42%]), LPA (285.6 min [20%]), and MVPA (22.5 min [2%]). In the model using three isometric log-ratio (ilr) coordinates, only one coordinate was statistically significant, suggesting that a specific aspect of the 24-hour activity composition was associated with glucose response. Reallocating 30 minutes from SED to LPA or sleep was associated with estimated reductions in glucose levels of -2.33 mg/dL (95% CI: -4.41, -0.26) and -1.27 mg/dL (95% CI: -2.22, -0.33), respectively.
CONCLUSION: These findings suggest that reducing SED time and reallocating to LPA and sleep may contribute to improved glucose regulation during the second trimester of pregnancy.
Details
- Title: Subtitle
- Associations Between 24-hour Activity And Glycemic Response During The Second Trimester Of Pregnancy: 2547
- Creators
- Alex Crisp - University of Iowa, Health, Sport, and Human PhysiologyJaemyung Kim - University of IowaBethany Barone Gibbs - West Virginia UniversityKara M. Whitaker - University of Iowa
- Resource Type
- Abstract
- Publication Details
- Medicine and science in sports and exercise, Vol.57(10S), pp.816-817
- DOI
- 10.1249/01.mss.0001161960.67420.ef
- ISSN
- 0195-9131
- eISSN
- 1530-0315
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Number of pages
- 2
- Grant note
R01HL153095
- Language
- English
- Date published
- 10/2025
- Academic Unit
- Epidemiology; Health, Sport, and Human Physiology
- Record Identifier
- 9984963627802771
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