Abstract
CKD Awareness and Risk Factor Control in US Adults: Findings from NHANES, 2009-2020: TH-PO1041
Journal of the American Society of Nephrology, Vol.36(10S)
10/2025
DOI: 10.1681/ASN.2025vmw07z7e
Abstract
Background:
Chronic kidney disease (CKD) is a major global health concern. Contemporary management focuses on risk factor control to limit progression to kidney failure. Yet, nearly 90% of individuals with CKD in the US are unaware of their diagnosis—missing opportunities for intervention. This study examines risk factor control and clinical management in individuals with CKD, comparing those aware vs. unaware using National Health and Nutrition Examination Survey (NHANES) data.
Methods:
Baseline characteristics were compared by CKD awareness. The proportion aware was evaluated overall, across CKD stages, and across NHANES cycles. Univariate and multivariable logistic regression analyses estimated the odds of achieving each risk factor control or medication use, comparing those aware vs. unaware.
Results:
In pooled NHANES samples, only 10.1% were aware of CKD. Awareness increased with worsening eGFR and albuminuria. Among those with CKD G4/G5, only 51% were aware. In crude models, factors positively associated with CKD awareness included statin use (OR = 2.07, 95% CI 1.68–2.56), RASi use (OR = 1.94, 95% CI 1.51–2.48), and LDL-C control <160 mg/dL (OR = 1.95, 95% CI 1.06–3.59). When modeling interactions with hypertension, diabetes, and CHD, CKD awareness was significantly associated with RAAS inhibitor use (OR = 3.63, 95% CI 1.23–10.70) and HbA1c control <8.0% (OR = 5.93, 95% CI 1.11–31.72).
Conclusion:
Despite increased awareness with increased CKD severity, awareness of CKD remains remarkably low. Those aware of CKD are likely to be aware of other conditions. Risk factor control were similar in those aware and not aware of their CKD with the exception of use of RAAS blockade which was more likely in those aware of CKD.
Details
- Title: Subtitle
- CKD Awareness and Risk Factor Control in US Adults: Findings from NHANES, 2009-2020: TH-PO1041
- Creators
- Timothy Michael ChowJunichi Ishigami
- Resource Type
- Abstract
- Publication Details
- Journal of the American Society of Nephrology, Vol.36(10S)
- DOI
- 10.1681/ASN.2025vmw07z7e
- ISSN
- 1046-6673
- eISSN
- 1533-3450
- Publisher
- American Society of Nephrology
- Language
- English
- Date published
- 10/2025
- Academic Unit
- Internal Medicine
- Record Identifier
- 9985016424202771
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