ChemInform Abstract: SYNTHESIS, X‐RAY CRYSTALLOGRAPHIC DETERMINATION, AND OPIOID ACTIVITY OF ERYTHRO‐5‐METHYLMETHADONE ENANTIOMERS. EVIDENCE WHICH SUGGESTS THAT μ AND Δ OPIOID RECEPTORS POSSESS DIFFERENT STEREOCHEMICAL REQUIREMENTS

P. S. Portoghese; J. H. Poupaert; D. L. Larson; W. C. Groutas; G. D. Meitzner; D. C. Swenson; G. D. Smith; W. L. Duax

doi:10.1002/chin.198246154

Abstract

ChemInform Abstract: SYNTHESIS, X‐RAY CRYSTALLOGRAPHIC DETERMINATION, AND OPIOID ACTIVITY OF ERYTHRO‐5‐METHYLMETHADONE ENANTIOMERS. EVIDENCE WHICH SUGGESTS THAT μ AND Δ OPIOID RECEPTORS POSSESS DIFFERENT STEREOCHEMICAL REQUIREMENTS

P. S. Portoghese, J. H. Poupaert, D. L. Larson, W. C. Groutas, G. D. Meitzner, D. C. Swenson, G. D. Smith and W. L. Duax

Chemischer Informationsdienst, Vol.13(46)

11/16/1982

DOI: 10.1002/chin.198246154

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Abstract

Die mit Hilfe von Di‐p‐toluoyl‐D‐weinsäure aus racemischem Dimethylaminobutanol (I) hergestellten Enantiomeren werden mit Diphenylessigester (II) zu den optisch aktiven Valeraten (III) kondensiert und mit Lithiumethyl zu den optischen Isomeren des 4,4‐Diphenyl‐5‐methyl‐6‐(dimethylamino)‐3‐heptanons (IV) umgesetzt.

diphenylmethane derivatives

Details

Title: Subtitle: ChemInform Abstract: SYNTHESIS, X‐RAY CRYSTALLOGRAPHIC DETERMINATION, AND OPIOID ACTIVITY OF ERYTHRO‐5‐METHYLMETHADONE ENANTIOMERS. EVIDENCE WHICH SUGGESTS THAT μ AND Δ OPIOID RECEPTORS POSSESS DIFFERENT STEREOCHEMICAL REQUIREMENTS
Creators: P. S. Portoghese
J. H. Poupaert
D. L. Larson
W. C. Groutas
G. D. Meitzner
D. C. Swenson
G. D. Smith
W. L. Duax
Resource Type: Abstract
Publication Details: Chemischer Informationsdienst, Vol.13(46)
Publisher: WILEY‐VCH Verlag GmbH
DOI: 10.1002/chin.198246154
ISSN: 0009-2975
eISSN: 2199-2924
Number of pages: 1
Language: English
Date published: 11/16/1982
Academic Unit: Chemistry
Record Identifier: 9984635116402771

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