Abstract
Clinicopathological description of a subset of schistosoma mansoni associated colorectal cancer patients in an endemic area in Brazil
Journal of clinical oncology, Vol.37(15_suppl), pp.e15154-e15154
05/20/2019
DOI: 10.1200/JCO.2019.37.15_suppl.e15154
Abstract
Abstract only e15154 Background: Schistosoma have been implicated in colorectal carcinogenesis. We aim to describe clinicopathological description of a subset of Schistosoma mansoni-associated colorectal cancer patients in an endemic area in Brazil. Methods: We have performed a survey at cancer registry and identified those colorectal cancer patients who underwent biopsy and/or surgery in our institution in the last 10 years. We performed a comparison between Schistosoma- and non-Schistosoma colorectal cancer patients. T-test were performed to compare clinico-pathological features. Results: 300 hundred patients were identified. From this population, 83 patients had encounters at gastroenterology unit, where schistosoma patients (among those with other diseases) are treated. Among them, 7 patients presented both conditions (colorectal cancer and schistosomiasis), corresponding to 8.4% of these selected population. We identified diferences among Schistosoma- and non-Schistosoma colorectal patients neither in age of cancer diagnosis nor in terms of laterality. We did not find diferences in terms of metastatic disease rate between both populations, however, we have observed a higher incidence of limph node metastasis among Schistosoma colorectal patients. Conclusions: Schistosoma colorectal patients present similarity in terms of age of cancer diagnosis and laterality when compared to non-Schistosoma colorectal patients, however, lymph node metastasis are increased in this population. Next publications from our group will provide information about survival curves and genetic profile.
Details
- Title: Subtitle
- Clinicopathological description of a subset of schistosoma mansoni associated colorectal cancer patients in an endemic area in Brazil
- Creators
- Gustavo Fernandes Godoy AlmeidaMauricio Assuero Lima de Freitas - FADE Federal University of Pernambuco, Recife, BrazilMariana M M Lira - Universidade Federal de PernambucoAna Lucia Coutinho Domingues - Universidade Federal de PernambucoLais Neares - Universidade Federal de PernambucoLauro Vinicius Machado da Silva - Centro Universitario Mauricio de Nassau, Recife, BrazilMaxwell Moura - Federal University of Pernambuco, Recife, BrazilMarcelo Maior - Hospital Das Clinicas Federal University of Pernambuco, Recife, BrazilLuiz Alberto Reis Mattos - Hospital das Clínicas da Universidade Federal de PernambucoAdvanced Support for Quality-of-life in Oncology (ASQO)
- Resource Type
- Abstract
- Publication Details
- Journal of clinical oncology, Vol.37(15_suppl), pp.e15154-e15154
- DOI
- 10.1200/JCO.2019.37.15_suppl.e15154
- ISSN
- 0732-183X
- eISSN
- 1527-7755
- Publisher
- AMER SOC CLINICAL ONCOLOGY; ALEXANDRIA
- Language
- English
- Date published
- 05/20/2019
- Academic Unit
- Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
- Record Identifier
- 9985150646902771
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