Abstract
Comparison of Airflows in Weibel-based and CT-based Human Lung Geometries
Annual Meeting of the APS Division of Fluid Dynamics, 57th (Seattle, Washington, 11/21/2004 - 11/23/2004)
11/22/2004
Abstract
The need for patient specific lung geometry for study of pulmonary air flow and drug delivery has been emphasized recently due to the complexity of individual airway tree geometry. The objective of this paper is to assess the notion of patient specific geometry by comparing airflows in an idealized Weibel-based lung model and two realistic human lung geometries. The Weibel-based model is composed of cylinders of differing diameters for various branching and has been used extensively for modeling airflow in lungs. Here a 4-generation Weibel model is considered. The realistic lung geometries are segmented and reconstructured from computerized tomography (CT) images as part of an effort to build a normative atlas (NIH HL-04368) documenting airway geometry over 4 decades of age in healthy and disease-state adult humans. The custom developed Taylor-Galerkin finite element code, which solves the incompressible Navier-Stokes equations, is applied to simulate airflows in these lung geometries. The velocity wave form recorded from a mechanical ventilator is adopted as the inlet pulsatile boundary condition. At the outlets, both the pressure and outflow boundary conditions are applied and compared. The counter-rotating vortices are observed in the Weibel model during both the inspiratory and expiratory cycles, being consistent with previous studies. The flow structures in the CT-based models are much more complicated and counter-rotating vortices are only evident in some regions.
Details
- Title: Subtitle
- Comparison of Airflows in Weibel-based and CT-based Human Lung Geometries
- Creators
- Ching-Long Lin (Author) - University of Iowa, Mechanical EngineeringEric A Hoffman (Author) - University of Iowa, Radiology
- Resource Type
- Abstract
- Conference
- Annual Meeting of the APS Division of Fluid Dynamics, 57th (Seattle, Washington, 11/21/2004 - 11/23/2004)
- Language
- English
- Date published
- 11/22/2004
- Academic Unit
- Mechanical Engineering; Radiology; Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9984564952202771
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