Abstract
E-064 Predicting symptomatic presentation of intracranial aneurysms using radiomics
Journal of neurointerventional surgery, Vol.16(Suppl 1), pp.A120-A121
07/21/2024
DOI: 10.1136/jnis-2024-SNIS.169
Abstract
BackgroundRadiomics is a novel image analysis tool that offers a voxel by voxel quantification of medical images signal, shape and texture characteristics. Our aim is to determine if radiomics analysis of intracranial aneurysms (IAs) can help predict their symptomatic presentation.MethodsPatients with >2 mm saccular aneurysms were imaged using a high-resolution vessel wall imaging 3T MRI at the University of Iowa. Symptomatic aneurysms were defined as IA presenting with cranial nerve palsy (e.g. III), rupture or sentinel headache. After co-registration of T1 and T1+Gd sequences, 3D Slicer was utilized to segment the aneurysms wall and extract radiomic features (figure 1). Machine learning was used to analyze the data in conjunction with the morphology and clinical variables to create predicting nomograms (figure 2).ResultsNinety patients with 104 IAs were included and 29 were defined as symptomatic. We selected 87 radiomic features that were significantly different between symptomatic and asymptomatic IAs. The clinical nomogram combining clinical, morphological and radiomic features achieved an AUC=0.83, 89% sensitivity and 73% specificity in predicting IAs symptomatic presentation.ConclusionsRadiomics may improve the prediction of IAs symptomatic presentation and may aid in the stratification of their risk of rupture. This information is essential to guide therapeutical management of unruptured IAs.Abstract E-064 Figure 13T HR-MRI image acquisition and segmentation in 3D slicerAbstract E-064 Figure 2Nomogram for symptomatic presentation predictionDisclosures A. Gudino: None. A. Saleem: None. C. Dier: None. E. Sagues: None. M. Torres: None. D. Ojeda: None. E. Garces: None. A. Vargas: None. C. Aamot: None. E. Samaniego: None.
Details
- Title: Subtitle
- E-064 Predicting symptomatic presentation of intracranial aneurysms using radiomics
- Creators
- A Gudino - University of IowaA Saleem - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAC Dier - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAE Sagues - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAM Torres - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAD Ojeda - University of IowaE Garces - Universidad San Francisco de QuitoA Vargas - University of Iowa, NeurologyC Aamot - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAE Samaniego - University of Iowa
- Resource Type
- Abstract
- Publication Details
- Journal of neurointerventional surgery, Vol.16(Suppl 1), pp.A120-A121
- DOI
- 10.1136/jnis-2024-SNIS.169
- ISSN
- 1759-8478
- eISSN
- 1759-8486
- Publisher
- BMJ Publishing Group Ltd
- Language
- English
- Date published
- 07/21/2024
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984687780302771
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