E-1 | In-hospital Outcomes after Percutaneous Coronary Intervention in Patients with Connective Tissue Disorders in the United States

Siddharth Agarwal; Agam Bansal; Charu Debnath; Satyam Krishan; Khawaja Hassan Akhtar; Ali Haider Jafry; Muhammad Faraz Anwaar; Nikita Garg; Sachin Saju; Vivian Pham; Usman Baber

doi:10.1016/j.jscai.2022.100261

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E-1 | In-hospital Outcomes after Percutaneous Coronary Intervention in Patients with Connective Tissue Disorders in the United States

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E-1 | In-hospital Outcomes after Percutaneous Coronary Intervention in Patients with Connective Tissue Disorders in the United States

Siddharth Agarwal, Agam Bansal, Charu Debnath, Satyam Krishan, Khawaja Hassan Akhtar, Ali Haider Jafry, Muhammad Faraz Anwaar, Nikita Garg, Sachin Saju, Vivian Pham, …

Journal of the Society for Cardiovascular Angiography & Interventions, Vol.1(3), 100261

05/2022

DOI: 10.1016/j.jscai.2022.100261

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Abstract

Background We aimed to assess the in-hospital outcomes in patients who underwent percutaneous coronary intervention (PCI) among patients with connective tissue disorders (CTD). Methods We utilized the Nationwide Inpatient Sample (NIS) from 2017–18. Primary outcome was in-hospital mortality. Secondary outcomes were stroke, acute kidney injury (AKI) requiring dialysis, vascular complications, major bleeding, total hospitalization charges and length of stay (LOS). Multivariate logistic regression was used to adjust for baseline characteristics. Results A total of 962,810 hospitalizations underwent PCI, of which 23,745 (2.46%) had underlying CTD. 59.6% were females among patients with CTD, vs 32.2% in the group without CTD (p<0.01). There was no difference in the in-hospital mortality in patients with CTD vs without CTD (2.7% vs 2.8%, p=0.58). Rate of AKI requiring dialysis (3.3% vs 2.9%, p=0.09) and stroke (0.9% vs 1%, p=0.67) did not differ significantly between the cohorts. Patients with CTD had a higher rate of major bleeding (1.8% vs 1.1%, p<0.01) and vascular complications (2.4% vs 1.5%, p<0.01). Presence of CTD was associated with longer LOS (4.5 vs 3.9 days, p<0.01), with no difference in the hospitalization charges. Multivariate analysis showed that patients with comorbid CTD had increased odds of post-procedural major bleeding and vascular complications (Figure 1), along with increased LOS (0.37 days longer, p<0.01). Conclusions Patients undergoing PCI with comorbid CTD have increased odds of developing post-procedure major bleeding, vascular complications along with longer LOS. No difference in the odds of mortality was observed.

Details

Title: Subtitle: E-1 | In-hospital Outcomes after Percutaneous Coronary Intervention in Patients with Connective Tissue Disorders in the United States
Creators: Siddharth Agarwal - University of Oklahoma Health Sciences Center
Agam Bansal - Cleveland Clinic
Charu Debnath - University of Oklahoma Health Sciences Center
Satyam Krishan - University of Oklahoma Health Sciences Center
Khawaja Hassan Akhtar - University of Oklahoma Health Sciences Center
Ali Haider Jafry - University of Oklahoma Health Sciences Center
Muhammad Faraz Anwaar - University of Oklahoma Health Sciences Center
Nikita Garg - Vardhman Mahavir Medical College & Safdarjung Hospital
Sachin Saju - University of Oklahoma Health Sciences Center
Vivian Pham - University of Oklahoma Health Sciences Center
Usman Baber - University of Oklahoma Health Sciences Center
Resource Type: Abstract
Publication Details: Journal of the Society for Cardiovascular Angiography & Interventions, Vol.1(3), 100261
DOI: 10.1016/j.jscai.2022.100261
ISSN: 2772-9303
eISSN: 2772-9303
Publisher: Elsevier Inc
Language: English
Date published: 05/2022
Academic Unit: Internal Medicine
Record Identifier: 9985222715602771

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