Abstract
E-106 Analysis of non-contrast computed tomography scans with radiomics to detect the hyperdense sign
Journal of neurointerventional surgery, Vol.16(Suppl 1), pp.A148-A149
07/21/2024
DOI: 10.1136/jnis-2024-SNIS.211
Abstract
Introduction The identification of the hyperdense artery sign (HAS) on non-contrast CT (NCCT) in acute ischemic strokes has traditionally relied on subjective visual evaluation. This study aims to explore the utilization of radiomics signal intensity (SI)-dependent features as an objective method for detecting HAS.Methods Patients who underwent endovascular therapy (EVT) for large vessel occlusion between 2022 and 2023 were included in this study. CT angiography (CTA) was employed to identify occlusions and estimate clot locations in NCCT. A Hounsfield Units (HU) ratio was calculated by comparing the affected side to the contralateral vessel, with strokes being considered to have HAS if the ratio exceeded 1.20. Subsequently, 3D Slicer was utilized to segment and extract radiomic SI features of the clot, including median and maximum values, measured in HU (figure 1). Stroke etiology was established based on the TOAST criteria at the last follow-up. The Mann-Whitney U test was employed to compare these SI features between strokes with and without HAS, and univariate logistic regression was used to study their relationship with stroke etiology. Results A total of 287 patients were included in our analysis, with 63% of strokes exhibiting HAS. Stroke etiology was 41% cardioembolic, 16% extracranial atherosclerotic disease, 7% intracranial atherosclerotic disease, with the remaining cases classified as cryptogenic. The SI radiomic features ‘median’ and ‘maximum’ were significantly higher in occlusions exhibiting HAS (56 and 71, respectively) compared to those without (49 and 63, respectively; p < 0.001). Moreover, the ‘maximum’ SI was significantly higher in strokes with a large vessel atherosclerotic etiology (p = 0.035). Conclusion Radiomics on NCCT may help quantify HAS and determine stroke etiology. The maximum SI in NCCT was higher in strokes with a large vessel atherosclerotic etiology.
Details
- Title: Subtitle
- E-106 Analysis of non-contrast computed tomography scans with radiomics to detect the hyperdense sign
- Creators
- A Gudino - University of IowaE Sagues - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAC Dier - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAE Garces - Universidad San Francisco de QuitoM Torres - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAD Ojeda - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAA Vargas - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAC Aamot - Neurology, University of Iowa Hospitals and Clinics, Iowa City, IAM Ghannam - University of IowaE Samaniego - University of Iowa
- Resource Type
- Abstract
- Publication Details
- Journal of neurointerventional surgery, Vol.16(Suppl 1), pp.A148-A149
- Publisher
- BMJ Publishing Group Ltd
- DOI
- 10.1136/jnis-2024-SNIS.211
- ISSN
- 1759-8478
- eISSN
- 1759-8486
- Language
- English
- Date published
- 07/21/2024
- Academic Unit
- Neurosurgery; Radiology; Neurology; Iowa Neuroscience Institute
- Record Identifier
- 9984688448302771
Metrics
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