Abstract
Effect of vocal fold tissue shear properties on phonation threshold pressure in a physical model of the larynx
The Journal of the Acoustical Society of America, Vol.107(5_Supplement), pp.2906-2906
05/01/2000
DOI: 10.1121/1.428815
Abstract
Previous analytical studies have shown that phonation threshold pressure (Pth), the minimum subglottal pressure required to initiate and sustain vocal fold oscillation, is directly related to the viscous shear properties (dynamic viscosity or viscous shear modulus) of the vocal fold mucosa in vibration [Titze, J. Acoust. Soc. Am. 83, 1536–1552 (1988); Chan, Ph.D. dissertation (1998)]. This relationship was verified empirically with a physical model of the larynx [Titze et al., J. Acoust. Soc. Am. 97, 3080–3084 (1995)], but no biological materials were tested in that study. This study attempted to establish the effects of biologically based tissue shear properties on Pth. Biomaterials with varying viscoelastic shear properties (abdominal subcutaneous fat, 0.01%–1.0% hyaluronic acid, and hyaluronic acid mixed with fibronectin) were incorporated into the artificial vocal fold mucosa of the physical model and self-sustained oscillation was induced. Results showed that no stable phonation could be established for fat, while higher Pth were consistently observed for higher concentrations of hyaluronic acid (with or without fibronectin), in correlation with their differences in viscous shear properties. These findings support the notion that hyaluronic acid could potentially be an optimal surgical bioimplant for the vocal fold mucosa, because it likely facilitates the ease of phonation. [Work supported by NIDCD.]
Details
- Title: Subtitle
- Effect of vocal fold tissue shear properties on phonation threshold pressure in a physical model of the larynx
- Creators
- Roger Chan - University of IowaIngo Titze - University of Iowa
- Resource Type
- Abstract
- Publication Details
- The Journal of the Acoustical Society of America, Vol.107(5_Supplement), pp.2906-2906
- DOI
- 10.1121/1.428815
- ISSN
- 0001-4966
- eISSN
- 1520-8524
- Language
- English
- Date published
- 05/01/2000
- Academic Unit
- School of Music; Communication Sciences and Disorders
- Record Identifier
- 9984719564902771
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