Abstract
Evaluating Mortality Trends In Heart Failure Patients With Coexisting Chronic Obstructive Pulmonary Disease (1999-2020)
Journal of cardiac failure, Vol.32(1), p.191
01/2026
DOI: 10.1016/j.cardfail.2025.11.048
Abstract
Introduction
Chronic obstructive pulmonary disease (COPD) and heart failure (HF) frequently coexist, with COPD exacerbating cardiovascular complications and increasing mortality risk. This study analyzes CDC WONDER data (1999-2020) to examine trends in HF mortality among patients with COPD, highlighting age-related disparities and patterns that can inform public health strategies.
Methods
Using CDC WONDER data, we calculated AAMR per 100,000 for individuals aged 45-64 and 65+ who died from heart failure (HF) with chronic obstructive pulmonary disease (COPD). MCD analysis included HF (I50.0, I50.1, I50.9) and COPD (J40-J44.9). Joinpoint regression estimated APC and AAPC from 1999 to 2020.
Results
From 1999 to 2009, the AAMR for heart failure with COPD declined from 43.998 to 39.575 before increasing steadily, reaching 50.656 in 2020 (AAPC: 0.53, 95% CI: 0.22 to 0.85). A total of 1,109,491 deaths were recorded, with males (54.08) having higher AAMRs than females (36.22). NH White had the highest AAMR (47.31), followed by American Indian/Alaska Natives (43.9), NH Black (34.36), Hispanic (20.15) and NH Asian/Pacific Islanders (12.13). Mortality was higher in non-metropolitan (59.60) vs. metropolitan areas (39.81) and varied regionally (Midwest: 49.8; South: 44.8; West: 41.4; Northeast: 35.4). California had the most deaths (111,051), with most nationwide (375,021) occurring in medical inpatients. Mortality peaked in the 65+ group (CMR: 108.4).
Conclusion
Heart failure mortality among COPD patients increased from 1999 to 2020, with disparities by sex, race, and region. Higher mortality rates were observed in older adults, non-metropolitan areas, and NH White individuals. The rise in 2020 highlights the need for targeted interventions to improve outcomes in high-risk populations.
Details
- Title: Subtitle
- Evaluating Mortality Trends In Heart Failure Patients With Coexisting Chronic Obstructive Pulmonary Disease (1999-2020)
- Creators
- Muhammad Usman HaiderRahul PatelDaniah RizwanIshtiaq AhmadIqra KhanFahad SaleemMian Zahid Jan KakakhelZaryab BachaMaryam TariqMustafa AlsaadiZaraq KhanVyom Patel
- Resource Type
- Abstract
- Publication Details
- Journal of cardiac failure, Vol.32(1), p.191
- DOI
- 10.1016/j.cardfail.2025.11.048
- ISSN
- 1071-9164
- Publisher
- Elsevier
- Language
- English
- Date published
- 01/2026
- Academic Unit
- Internal Medicine
- Record Identifier
- 9985129576402771
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