FIBROCALCIFIC AORTIC VALVE DISEASE IN MICE IS DEPENDENT UPON BOTH ENDOTHELIAL NITRIC OXIDE SYNTHASE GENOTYPE AND VALVE CUSP NUMBER

Ramzi El Accaoui; Georges Hajj; Melissa Davis; Yi Chu; Donald Lund; Robert Brooks; Diane Kraft; Kathy Zimmerman; Donald Heistad; Robert Weiss

doi:10.1016/S0735-1097(12)62014-2

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FIBROCALCIFIC AORTIC VALVE DISEASE IN MICE IS DEPENDENT UPON BOTH ENDOTHELIAL NITRIC OXIDE SYNTHASE GENOTYPE AND VALVE CUSP NUMBER

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FIBROCALCIFIC AORTIC VALVE DISEASE IN MICE IS DEPENDENT UPON BOTH ENDOTHELIAL NITRIC OXIDE SYNTHASE GENOTYPE AND VALVE CUSP NUMBER

Ramzi El Accaoui, Georges Hajj, Melissa Davis, Yi Chu, Donald Lund, Robert Brooks, Diane Kraft, Kathy Zimmerman, Donald Heistad and Robert Weiss

Journal of the American College of Cardiology, Vol.59(13), pp.E2013-E2013

03/27/2012

DOI: 10.1016/S0735-1097(12)62014-2

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Abstract

Background Clinical risk factors for fibrocalcific aortic valve disease are associated with decreased bioavailability of endothelium-derived nitric oxide (EDNO).

Calcification

Genotype & phenotype

Medical research

Nitric oxide

Rodents

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Title: Subtitle: FIBROCALCIFIC AORTIC VALVE DISEASE IN MICE IS DEPENDENT UPON BOTH ENDOTHELIAL NITRIC OXIDE SYNTHASE GENOTYPE AND VALVE CUSP NUMBER
Creators: Ramzi El Accaoui
Georges Hajj
Melissa Davis
Yi Chu
Donald Lund
Robert Brooks
Diane Kraft
Kathy Zimmerman
Donald Heistad
Robert Weiss
Resource Type: Abstract
Publication Details: Journal of the American College of Cardiology, Vol.59(13), pp.E2013-E2013
Publisher: Elsevier Limited
DOI: 10.1016/S0735-1097(12)62014-2
ISSN: 0735-1097
eISSN: 1558-3597
Language: English
Date published: 03/27/2012
Academic Unit: Neuroscience and Pharmacology; Cardiovascular Medicine; Radiology; Internal Medicine
Record Identifier: 9984303992302771

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