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IP58-01 PREOPERATIVE URINALYSIS AND URINE CULTURE DO NOT IMPACT DEVICE INFECTION RATES AFTER PENILE PROSTHESIS PLACEMENT
Abstract   Peer reviewed

IP58-01 PREOPERATIVE URINALYSIS AND URINE CULTURE DO NOT IMPACT DEVICE INFECTION RATES AFTER PENILE PROSTHESIS PLACEMENT

Alexandria M. Hertz, Harlee Possoit, Jonathan Seaman, Maali La France, Aziz Shabaan, Ryan Hanson, Steven Hudak and Maia Van Dyke
The Journal of urology, Vol.215(5S), p.e1165
05/2026
DOI: 10.1097/01.JU.0001191628.19015.5e.01

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Abstract

INTRODUCTION AND OBJECTIVES: Device infection is a devastating complication of penile prosthesis (PP) implantation. Abundant studies have evaluated various risk factors for infection. Controversy exists as to the potential impact of urinary tract colonization on device infection risk. The objective of this study is to evaluate the impact of preoperative urinalysis (UA) or urine culture (UCx) on postoperative PP infection. METHODS: A retrospective cohort study of all patients undergoing PP placement or revision at a single institution between January 2016 and March 2025 was performed. Urethral catheterization is routinely used at our institution, with the catheter placed immediately prior to skin incision and removed either at the end of the case or within 24 hours. Demographic, preoperative testing, and postoperative infection data were reviewed. A positive UCx was defined as >100K CFU of bacterial growth and postoperative infection was defined as explant at any point post-operatively. Preoperative tested (UA vs. UCx) vs. non-tested cohorts were compared using Chi-square/Fischer Exact test, t-test, and logistic regression. RESULTS: A total of 897 cases were performed by one of three fellowship trained surgeons during the time period evaluated. The overall PP infection rate was 2.3% (21/897). Median age was 66, median BMI was 28.7, 14.83% of patients had a history of radiation, 26.1% of cases were revisions, and 34.2% of patients had diabetes. Preoperative UA was obtained in 27.4% (246/897), UCx in 22.9% (205/897), and 65.7% (589/897) had no preoperative urine testing. There was no difference in the rate of postoperative PP infection between these three groups (3.3% vs. 1.9% vs. 2.2%, p=0.481). Of the 205 patients with a preoperative UCx, 31 were positive (15.1%), 10 of whom were treated with preoperative antibiotics. None of the pretreated patients developed an infection, but one of the 21 UCx positive-untreated patients developed an infection (0.0% vs. 4.8%, p=1). CONCLUSIONS: Postoperative PP infection rates do not appear to be impacted by preoperative urinalysis and/or urine culture, calling into question the need for routine preoperative urine testing prior to PP placement.

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