Imaging spectrum of medical refractory temporal lobe epilepsy on PET and MRI with pathologic correlation

Pankaj Watal; Karra Jones; Eunkyung Park; Sarv Priya; Yusuf Menda

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$Imaging spectrum of medical refractory temporal lobe epilepsy on PET and MRI with pathologic correlation$

Abstract

Peer reviewed

Imaging spectrum of medical refractory temporal lobe epilepsy on PET and MRI with pathologic correlation

Pankaj Watal, Karra Jones, Eunkyung Park, Sarv Priya and Yusuf Menda

The Journal of nuclear medicine (1978), Vol.59, p.1207

05/01/2018

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Abstract

Objectives: Imaging of Temporal lobe epilepsy with PET and MRI: A Correlation with Surgical Pathology Learning Objectives: 1. Recognize the imaging findings of PET and MRI in preoperative localization of temporal lobe epilepsy. 2. Examine how imaging findings correlate with the histopathological features and International League Against Epilepsy (ILAE) pathological classification schema. Summary: This review will demonstrate the spectrum of preoperative PET and MRI imaging features in patient with medical refractory temporal lobe epilepsy (TLE) with histopathologic correlation. The review is based on retrospective evaluation of 78 patients who underwent surgery for treatment of refractory TLE at our institution since 2000, with at least one preoperative MRI and one interictal PET within one year prior to surgery. The patients were broadly classified into 4 groups based on the neuropathologic pattern: Focal cortical dysplasia (FCD) group, isolated or coexistent with other epileptogenic lesions; second group with neoplastic lesions; third group with Isolated hippocampal sclerosis and a fourth group of nonspecific gliosis (not meeting criteria for hippocampal sclerosis or FCD). The PET and MRI imaging patterns of each of these groups will be reviewed in correlation with pathology after surgery.

Brain

Epilepsy

Magnetic Resonance Imaging

Medical Imaging

Nuclear Medicine

Pathology

Surgery

Correlation

Cortex

Dysplasia

Gliosis

Hippocampus

Lesions

Localization

Patients

Positron emission

Positron emission tomography

Sclerosis

Temporal lobe

Tomography

Details

Title: Subtitle: Imaging spectrum of medical refractory temporal lobe epilepsy on PET and MRI with pathologic correlation
Creators: Pankaj Watal
Karra Jones
Eunkyung Park
Sarv Priya
Yusuf Menda
Resource Type: Abstract
Publication Details: The Journal of nuclear medicine (1978), Vol.59, p.1207
Publisher: Society of Nuclear Medicine
ISSN: 0161-5505
eISSN: 1535-5667
Language: English
Date published: 05/01/2018
Academic Unit: Radiology; Radiation Oncology
Record Identifier: 9984314288502771

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