Abstract
Impact of Weight on Breast and Cervical Cancer Treatment Quality
Obesity (Silver Spring, Md.), Vol.30, pp.265-265
11/01/2022
Abstract
Background: Obesity is associated with increased cancer-specific mortality, and lower cancer survival. Timely access to high quality, evidence-based cancer treatment is known to impact outcomes; however, we do not know whether these vary by weight. Methods: We used data from the Iowa Cancer Registry (2006-2015), linked with drivers license data for height and weight, to examine whether treatment type, and time from cancer diagnosis to treatment initiation varied by BMI category. We evaluated whether adherence to Commission on Cancer treatment guidelines varied by BMI. Finally, we assessed associations of BMI with cancer survival, and explored whether timely or guideline concordant care modified associations between BMI and survival outcomes. Results: During the period 2006-2015, there were 19,102 breast cancer patients, and 911 cervical cancer patients with drivers licenselinked data in the Iowa Cancer Registry. Breast cancer patients with obesity were less likely to receive a contralateral prophylactic mastectomy or breast reconstruction than patients with a BMI of 18.5-24.9 kg/m2. Time from diagnosis to receipt of surgery, chemotherapy and hormone therapy increased with BMI. Cervical cancer patients with obesity were less likely to receive surgery, and more likely to receive chemotherapy than patients with a BMI of 18.5-24.9 kg/m2. They also had a shorter time to chemotherapy; however, time to radiation and surgical treatment was higher among those with a BMI of 25-29 and 30-35 kg/m2. Conclusions: This study is the first to use cancer registry data to investigate whether receipt of timely or guideline-concordant cancer treatment was associated with obesity among breast and cervical cancer patients. Our preliminary results indicate that there may be differences in cancer treatment by weight that require further investigation. Ongoing work by our group is exploring the potential role of weight stigma in receipt of timely and guideline-concordant cancer care.
Details
- Title: Subtitle
- Impact of Weight on Breast and Cervical Cancer Treatment Quality
- Creators
- Sarah NashKathleen RobinsonIngrid LizarragaKeely UlmerAmanda KahlMary Charlton
- Resource Type
- Abstract
- Publication Details
- Obesity (Silver Spring, Md.), Vol.30, pp.265-265
- Publisher
- Blackwell Publishing Ltd
- ISSN
- 1930-7381
- eISSN
- 1930-739X
- Comment
- DOI for all abstracts: 10.1002/oby.23626
- Language
- English
- Date published
- 11/01/2022
- Academic Unit
- Epidemiology; Surgery; Obstetrics and Gynecology; Community and Behavioral Health; Center for Social Science Innovation
- Record Identifier
- 9984338984902771
Metrics
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