OBSTRUCTIVE SLEEP APNEA PREDICTS RECURRENCE OF ATRIAL ARRHYTHMIAS FOLLOWING CRYOBALLOON ABLATION IN PATIENTS WITH PAROXYSMAL ATRIAL FIBRILLATION

Abhishek Bose; Parag Anilkumar Chevli; Zeba Hashmath; Ajay K. Mishra; Gregory Berberian; Ghasan Ahmad; Jerzy Januszkiewicz; Hafiz Ghafoor; Douglas Laidlaw

doi:10.1016/S0735-1097(20)31083-4

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OBSTRUCTIVE SLEEP APNEA PREDICTS RECURRENCE OF ATRIAL ARRHYTHMIAS FOLLOWING CRYOBALLOON ABLATION IN PATIENTS WITH PAROXYSMAL ATRIAL FIBRILLATION

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OBSTRUCTIVE SLEEP APNEA PREDICTS RECURRENCE OF ATRIAL ARRHYTHMIAS FOLLOWING CRYOBALLOON ABLATION IN PATIENTS WITH PAROXYSMAL ATRIAL FIBRILLATION

Abhishek Bose, Parag Anilkumar Chevli, Zeba Hashmath, Ajay K. Mishra, Gregory Berberian, Ghasan Ahmad, Jerzy Januszkiewicz, Hafiz Ghafoor and Douglas Laidlaw

Journal of the American College of Cardiology, Vol.75(11 Suppl 1), pp.456-456

03/24/2020

DOI: 10.1016/S0735-1097(20)31083-4

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Abstract

Background In spite of acute pulmonary vein isolation in cryoballoon ablation (CBA) for paroxysmal atrial fibrillation (AF), about one third of patients have recurrence of atrial arrhythmias (AA). Presence of obstructive sleep apnea (OSA) is a known risk factor for development of AF. However, the role of OSA as a predictor of recurrence of AA following CBA for paroxysmal AF is unclear. Methods We followed 76 (Age 60.7±9.4, 30% women) patients undergoing CBA for one year post procedure for development of any AA. Evidence of recurrence was assessed by documented AA on EKG or any form of long term cardiac rhythm monitoring. Presence of OSA as a predictor of recurrence was evaluated in a multivariate cox proportional hazard model. Results After a one year follow up, 15 (19.7%) patients developed recurrence of AA. The study population was divided into two groups based on presence or absence of OSA. Baseline demographics were similar between the two groups. On a multivariate cox proportional hazard model adjusted for baseline demographics and risk factors for development of AF, presence of OSA was a significant predictor for recurrence of AA following CBA (Table, p=0.04). Additionally, on Kaplan-Meier analysis presence of OSA was an independent predictor for recurrence of AA following CBA (Figure). Conclusion Presence of OSA independently predicts failure of CBA for paroxysmal AF. Screening for undiagnosed OSA in patients with paroxysmal AF may help select the ideal candidates likely to benefit from CBA.

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Title: Subtitle: OBSTRUCTIVE SLEEP APNEA PREDICTS RECURRENCE OF ATRIAL ARRHYTHMIAS FOLLOWING CRYOBALLOON ABLATION IN PATIENTS WITH PAROXYSMAL ATRIAL FIBRILLATION
Creators: Abhishek Bose - Saint Vincent Hospital
Parag Anilkumar Chevli - Saint Vincent Hospital
Zeba Hashmath - Saint Vincent Hospital
Ajay K. Mishra - Saint Vincent Hospital
Gregory Berberian - Saint Vincent Hospital
Ghasan Ahmad - Saint Vincent Hospital
Jerzy Januszkiewicz - Saint Vincent Hospital
Hafiz Ghafoor - Saint Vincent Hospital
Douglas Laidlaw - Saint Vincent Hospital
Resource Type: Abstract
Publication Details: Journal of the American College of Cardiology, Vol.75(11 Suppl 1), pp.456-456
DOI: 10.1016/S0735-1097(20)31083-4
ISSN: 0735-1097
Language: English
Date published: 03/24/2020
Academic Unit: Internal Medicine
Record Identifier: 9985222832102771

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