Abstract
OC4-01 Vibration Exposure Limits for Neurotrauma Patients During Medical Transport: Overview
Journal of Neurotrauma, Vol.31(12), p.A-13
06/17/2014
Abstract
Anecdotal observations in the field reported severe pain experienced by neurotrauma patients when subjected to bumpy and high vibration ground and air medical transport. The literature indicates that vehicle vibration due to medical transport may be affecting medical outcomes. The goals of our efforts are to (1) Characterize the effects of transport on a swine model of traumatic brain injury (TBI) and spinal cord injury (SCI), (2)Characterize the healthy human biodynamic response under similar transport modes, (3) Identify TBI/SCI biomarkers from behavioral, histological, imaging, and physiological measures, and (4) Develop the dose-response relationship and determine the vibration exposure limit for injured humans. The TBI mechanism is accomplished through blast exposure and the SCI is produced surgically similar to the University of British Columbia model. The TBI/SCI model is exposed to realistic ground and air medical transport scenarios. The tested animals are divided into four groups: (1) sham group, (2) TBI/SCI+transport, (3) TBI/SCI and 4) SCI+transport. Standard military medical transport procedures are practiced for immobilizing and securing the TBI/SCI model. Physiological measurements and vehicle vibration throughout the patient litter support system to include the animal model are recorded. X-ray images, MRI, and neurologic evaluation are conducted before and after each exposure. Various immunohistochemical and other CNS stains are used to validate astrocyte-released injury biomarkers in swine CSF. Vibration transmissibility of the patient support system in a military helicopter is measured using supine healthy humans. The transfer functions measured for the injured animals and the healthy humans are trans-formed to determine vibration exposure limit criteria relevant to neurotrauma patient transport.
Details
- Title: Subtitle
- OC4-01 Vibration Exposure Limits for Neurotrauma Patients During Medical Transport: Overview
- Creators
- K BarazanjiA MayerR KinslerI WannerA MatchettS Rahmatalla - University of Iowa, Civil and Environmental EngineeringD Wilder - University of Iowa, Roy J. Carver Department of Biomedical EngineeringB KwonP CriptonP ChambersD Reynolds
- Resource Type
- Abstract
- Publication Details
- Journal of Neurotrauma, Vol.31(12), p.A-13
- Comment
- DOI: 10.1089/neu.2014.9935.abstracts. Abstracts from The 32nd Annual National Neurotrauma SymposiumJune 29–July 2, 2014San Francisco, California. Journal of Neurotrauma.Jun 2014.A-1-A-126.
- Language
- English
- Date published
- 06/17/2014
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Civil and Environmental Engineering; Occupational and Environmental Health; Injury Prevention Research Center
- Record Identifier
- 9984064500202771
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