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PD30-03 CLINICAL SIGNIFICANCE OF CYSTOSCOPIC RECURRENCE AFTER ANTERIOR URETHROPLASTY. A MULTI-INSTITUTION ANALYSIS FROM TRAUMA AND UROLOGIC RECONSTRUCTIVE NETWORK OF SURGEONS (TURNS)
Abstract   Open access   Peer reviewed

PD30-03 CLINICAL SIGNIFICANCE OF CYSTOSCOPIC RECURRENCE AFTER ANTERIOR URETHROPLASTY. A MULTI-INSTITUTION ANALYSIS FROM TRAUMA AND UROLOGIC RECONSTRUCTIVE NETWORK OF SURGEONS (TURNS)

Nima Baradaran, Kirkpatrick Fergus, Thomas Gaither, Gregory Murphy, Sean Elliott, Jeremy Myers, Bryan Voelzke, Thomas Smith, Bradley Erickson, Nejd Alsikafi, …
The Journal of urology, Vol.199(4S), pp.e634-e635
04/2018
DOI: 10.1016/j.juro.2018.02.1522
url
https://doi.org/10.1016/j.juro.2018.02.1522View
Published (Version of record) Open Access

Abstract

INTRODUCTION AND OBJECTIVES Definition of ″success″ is debated in the anterior urethroplasty (AU) literature. Cystoscopic recurrence of stricture does not always correlate with patients′ symptoms or the need for an intervention. This study aims to assess the functional outcome of patients with a cystoscopic recurrence of stricture after AU. METHODS All cases with available cystoscopy data after AU in TURNS database were retrospectively studied. We assessed the cumulative probability of intervention (primary outcome) and the quality of life scores (secondary outcome) in association with cystoscopic recurrence. Patients with history of hypospadias, perineal urethrostomy, urethral fistula and meatal pathology were excluded. Kaplan-Meier failure estimate and log-rank test of equality were used to assess primary outcome; Kruskal Wallis test was used for secondary outcome. RESULTS From a total of 2309 AUs, 1054 patients met the inclusion criteria and were categorized as normal (n=740), recurrence >17 (n=178), and recurrence <17 (n=136) based on the first cystoscopic evaluation postoperatively. Patients with recurrence had longer preoperative stricture length and higher rate of lichen sclerosus diagnosis, radiation history, and use of graft. Cystoscopic recurrence was significantly associated with higher rate of secondary interventions (2.7%, 6.2%, 33% in normal, >17, and <17 groups respectively, figure 1). In the intervention-free subset, IPSS, SHIM, MSHQ and CLSS were not statistically significantly different among the three study groups (figure 2). CONCLUSIONS Many patients with cystoscopic recurrence are satisfied with their symptoms with no need for intervention. Cystoscopy may be a poor initial screening test for urethral stricture recurrence defined by patient symptoms and need for secondary interventions.

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