Abstract
PM2.5 CHEMICAL CONSTITUENTS AND MORTALITY IN 49 U.S. COMMUNITIES FROM 2001 TO 2005
Environmental health perspectives. Supplements, Vol.2011(1)
09/13/2011
DOI: 10.1289/isee.2011.00896
Abstract
Background and Aims: Short-term exposure to ambient particulate matter less than 2.5 µm in aerodynamic diameter (PM2.5) is consistently associated with adverse health outcomes in population studies. The PM2.5 mass represents a chemically diverse mixture of pollutants and there is limited evidence on the health effects of PM2.5 constituents.
Methods: We conducted a national multi-site time series analysis to examine the association between daily non-accidental mortality (≥ 65 years of age) and ambient levels of seven major PM2.5 chemical constituents: sulfate, elemental carbon (EC), nitrate, organic carbon (OC), silicon, sodium ion, and ammonium ion. Average lag-specific relative rates of death associated with each constituent were estimated using a two-stage Bayesian hierarchical model to combine evidence across 49 U.S. communities from 2001-2005.
Results: In a single pollutant model controlling for weather and seasonality, an interquartile range (IQR) increase in 2-day lagged EC levels (0.46 µg/m3) was associated with a 0.41% [95% posterior interval (PI), 0.06–0.76%] increase in the relative rate of death. An IQR increase in 1-day lagged OC levels (2.47 µg/m3) was associated with a 0.64% (95% PI, 0.14–1.15%) increase in the relative rate of death.
Conclusions: These findings suggest that ambient levels of EC and OC were positively associated with all-cause mortality for the elderly population. However, further investigations are needed to elucidate the joint effects of the PM2.5 constituents and their sources.
Details
- Title: Subtitle
- PM2.5 CHEMICAL CONSTITUENTS AND MORTALITY IN 49 U.S. COMMUNITIES FROM 2001 TO 2005
- Creators
- Lucas NeasHoward ChangMontserrat FuentesLisa BaxterLyle Burgoon
- Resource Type
- Abstract
- Publication Details
- Environmental health perspectives. Supplements, Vol.2011(1)
- DOI
- 10.1289/isee.2011.00896
- ISSN
- 1078-0475
- eISSN
- 2169-2181
- Language
- English
- Date published
- 09/13/2011
- Academic Unit
- Statistics and Actuarial Science; President; Biostatistics
- Record Identifier
- 9984065879502771
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