Abstract
PO-01-035 CATHETER ABLATION FOR ATRIAL TACHYARRHYTHMIAS IN ADULTS WITH FONTAN PALLIATION: A MULTICENTER STUDY FROM THE PEDIATRIC AND CONGENITAL ELECTROPHYSIOLOGY SOCIETY (PACES) AND INTERNATIONAL SOCIETY FOR ADULT CONGENITAL HEART DISEASE (ISACHD)
Heart rhythm, Vol.21(5 Supplement), pp.S215-S216
05/2024
DOI: 10.1016/j.hrthm.2024.03.694
Abstract
Background
Atrial tachyarrhythmias (AT) are a common late manifestation after Fontan palliation and contribute to significant morbidity and mortality. Outcomes of AT ablation in adults with Fontan palliation have not been broadly evaluated using current-era technologies.
Objective
Evaluate the outcomes of current era AT ablation in adults with total cavopulmonary connection (TCPC) Fontan from an international cohort.
Methods
A retrospective, PACES/ISACHD multi-site study was conducted on patients >18 years of age with TCPC Fontan who underwent catheter ablation for AT between 2012 and 2022. Data were securely electronically collected on cardiac history, ablation procedures, outcomes, and follow-up. Primary outcomes included: 1) acute successful ablation and 2) occurrence of AT during follow-up. Fisher’s Exact tests were used to assess between-group differences. Holm’s method was used to correct for multiple comparisons.
Results
A total of 200 procedures for patients median age 28 years, 131 lateral Fontan (68%), 43 (22%) extracardiac conduit, single systemic LV 112 (56%), were enrolled from 15 international centers. Procedure characteristics are described in Table 1. More than 1 tachycardia was demonstrated in 56%. Acute successful ablation was achieved in 91%. AT requiring intervention occurred in 51% at median follow up 0.58 years (IQR 0.1, 2.15) after ablation. The occurrence of AT during follow-up was not associated with ventricular function, type of Fontan, transbaffle access, AV valve regurgitation, heterotaxy, or more than one tachycardia at the ablation procedure. Use of a multi-electrode mapping catheter was associated with fewer AT requiring intervention during follow-up.
Conclusion
In the current era of adult TCPC Fontan patients, the acute success rate for catheter ablation of AT exceeds 90%. Nevertheless, the arrhythmia burden remains substantial post-ablation, with over 50% experiencing an AT that requires intervention.
Details
- Title: Subtitle
- PO-01-035 CATHETER ABLATION FOR ATRIAL TACHYARRHYTHMIAS IN ADULTS WITH FONTAN PALLIATION: A MULTICENTER STUDY FROM THE PEDIATRIC AND CONGENITAL ELECTROPHYSIOLOGY SOCIETY (PACES) AND INTERNATIONAL SOCIETY FOR ADULT CONGENITAL HEART DISEASE (ISACHD)
- Creators
- Anna N. KampJeremy P. MooreVictoria ShayChance AlvaradoScott R. CeresnakFrancis BessiereBenjamin HaleMartin J. LaPagePhilip M. ChangThomas A. PilcherOrhan U. KilincMohammad Al-mousilyJohannes C. von AlvenslebenAudrey DionneNatasja M. De GrootFrank A. FishPaul Khairy
- Resource Type
- Abstract
- Publication Details
- Heart rhythm, Vol.21(5 Supplement), pp.S215-S216
- DOI
- 10.1016/j.hrthm.2024.03.694
- ISSN
- 1547-5271
- eISSN
- 1556-3871
- Language
- English
- Date published
- 05/2024
- Academic Unit
- Cardiology; Stead Family Department of Pediatrics
- Record Identifier
- 9984701750202771
Metrics
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