PP01.118: Phase 1b/2 trial of BNT324/DB-1311 (B7H3 ADC) with Pumitamig (BNT327; PD-L1 x VEGF-A bsAb) in Lung Cancer (SCLC or NSCLC): BNT324-01 Trial in Progress

Adam Schoenfeld; Alexander Spira; Aaron E. Lisberg; Martin E. Gutierrez; Kamlesh Sankhala; Margaret Byrne; Karen L. Reckamp; Angel Qin; Thomas U. Marron; Kartik Konduri; Donald A. Richards; John Paschold; Clifton Layman; Erin L. Schenk; Kaushal Parikh; Yanyan Lou; Vinicius Ernani; Alex Adjei; Mehmet Altan; Yang Qiu; Hannah Fang; Hua Mu; Michael Pinho; Troy Reed; Melisa Soland; Raoul Tibes; Özlem Türeci; Ugur Sahin; Luis Paz-Ares

doi:10.1016/j.jtho.2026.103852

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PP01.118: Phase 1b/2 trial of BNT324/DB-1311 (B7H3 ADC) with Pumitamig (BNT327; PD-L1 x VEGF-A bsAb) in Lung Cancer (SCLC or NSCLC): BNT324-01 Trial in Progress

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PP01.118: Phase 1b/2 trial of BNT324/DB-1311 (B7H3 ADC) with Pumitamig (BNT327; PD-L1 x VEGF-A bsAb) in Lung Cancer (SCLC or NSCLC): BNT324-01 Trial in Progress

Adam Schoenfeld, Alexander Spira, Aaron E. Lisberg, Martin E. Gutierrez, Kamlesh Sankhala, Margaret Byrne, Karen L. Reckamp, Angel Qin, Thomas U. Marron, Kartik Konduri, …

Journal of thoracic oncology, Vol.21(5), 103852

05/2026

DOI: 10.1016/j.jtho.2026.103852

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Title: Subtitle: PP01.118: Phase 1b/2 trial of BNT324/DB-1311 (B7H3 ADC) with Pumitamig (BNT327; PD-L1 x VEGF-A bsAb) in Lung Cancer (SCLC or NSCLC): BNT324-01 Trial in Progress
Creators: Adam Schoenfeld - Memorial Sloan Kettering Cancer Center
Alexander Spira - Virginia Cancer Specialists
Aaron E. Lisberg - UCLA, Los Angeles, CA
Martin E. Gutierrez - John Theurer Cancer Center at Hackensack UMC, Hackensack, NJ
Kamlesh Sankhala - Precision NextGen Oncology and Research Center, Beverly Hills, CA
Margaret Byrne - University of Iowa
Karen L. Reckamp - Cedars-Sinai Medical Center
Angel Qin - U-M Rogel Cancer Center
Thomas U. Marron - Icahn School of Medicine at Mount Sinai
Kartik Konduri - Texas Oncology DFW, Dallas, TX
Donald A. Richards - Sarah Cannon Research Institute
John Paschold - Virginia Oncology Associates
Clifton Layman - NSF National eXtreme Ultrafast Science Facility
Erin L. Schenk - The Medical Center of Aurora
Kaushal Parikh - Mayo Clinic
Yanyan Lou - Mayo Clinic in Florida
Vinicius Ernani - Mayo Clinic in Arizona
Alex Adjei - Case Comprehensive Cancer Center
Mehmet Altan - MD Anderson Cancer Center, Houston, TX
Yang Qiu - Duality Biologics, Shanghai, CHINA
Hannah Fang - Duality Biologics, Shanghai, CHINA
Hua Mu - Duality Biologics, Shanghai, CHINA
Michael Pinho - BioNTech US Inc, Cambridge, MA
Troy Reed - BioNTech US Inc, Cambridge, MA
Melisa Soland - BioNTech US Inc, Cambridge, MA
Raoul Tibes - BioNTech SE, Mainz, GERMANY
Özlem Türeci - BioNTech SE, Mainz, GERMANY
Ugur Sahin - BioNTech SE, Mainz, GERMANY
Luis Paz-Ares - Hospital Universitario 12 De Octubre
Resource Type: Abstract
Publication Details: Journal of thoracic oncology, Vol.21(5), 103852
DOI: 10.1016/j.jtho.2026.103852
ISSN: 1556-0864
Publisher: Elsevier Inc
Language: English
Date published: 05/2026
Academic Unit: Internal Medicine
Record Identifier: 9985163700302771

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