Surgical Outcome of Invasive Anterior Skull Base Tumors

Kuniki Eguchi; Takaharu Tatsukawa; Satoshi Yamaguchi; Eiichiro Sakoda; Masaaki Takeda; Prabin Shrestha; Tsuyoshi Okubo; Katsuhiro Hirakawa; Kaoru Kurisu

doi:10.1055/s-2008-1093191

Abstract

Surgical Outcome of Invasive Anterior Skull Base Tumors

Kuniki Eguchi, Takaharu Tatsukawa, Satoshi Yamaguchi, Eiichiro Sakoda, Masaaki Takeda, Prabin Shrestha, Tsuyoshi Okubo, Katsuhiro Hirakawa and Kaoru Kurisu

Skull Base, Vol.18(S 01), p.A103

09/23/2008

DOI: 10.1055/s-2008-1093191

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Abstract

Surgery of anterior skull base tumors invading the dura mater is still challenging. In this surgery successful reconstruction is also crucial. We retrospectively reviewed outcome of anterior skull base tumors with dural invasion. Standard procedures are as follows. Following bifrontal craniotomy, basal frontal and transfacial/transnasal removal of the tumor is performed. Dural defect is reconstructed with free pericranial flap harvested beyond skin incision. Bony defect is covered with frontal-based monopedicled and/or bipedicled musculofasciopericranial flap, which is followed by reconstruction with vascularized free muscular flap in some cases. Results: Fifteen cases (age range, 23 to 75 years old). Mean follow-up period is 29 months (range, 3 to 106 months). Tumors consist of 11 malignant tumors including 5 esthesioneuroblastomas and 4 benign tumors. Total removal was achieved in all cases. One patient died from myocardial infarction just after surgery. Among surgical complications only brain abscess required drainage and second reconstruction of the frontal base. Five-year relapse-free survival of malignancy was 60%. Conclusions: Extirpation of anterior skull base tumors with safety margins and reconstruction for defects of the structures including the dura are effective for the tumors involving the dura. However, as many of those tumors present already in an advanced stage and the surgical insult can be enormous, it is necessary to deliberate carefully before choosing this surgery.

Details

Title: Subtitle: Surgical Outcome of Invasive Anterior Skull Base Tumors
Creators: Kuniki Eguchi - Hiroshima, Japan
Takaharu Tatsukawa - Hiroshima, Japan
Satoshi Yamaguchi - Hiroshima, Japan
Eiichiro Sakoda - Hiroshima, Japan
Masaaki Takeda - Hiroshima, Japan
Prabin Shrestha - Hiroshima, Japan
Tsuyoshi Okubo - Hiroshima, Japan
Katsuhiro Hirakawa - Hiroshima, Japan
Kaoru Kurisu - Hiroshima, Japan
Resource Type: Abstract
Publication Details: Skull Base, Vol.18(S 01), p.A103
DOI: 10.1055/s-2008-1093191
ISSN: 1531-5010
eISSN: 1532-0065
Language: English
Date published: 09/23/2008
Academic Unit: Neurosurgery
Record Identifier: 9984697053702771

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