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THE ROLE OF SMOKING ON CRYOBALLOON ABLATION OUTCOMES FOR PAROXYSMAL ATRIAL FIBRILLATION
Abstract   Peer reviewed

THE ROLE OF SMOKING ON CRYOBALLOON ABLATION OUTCOMES FOR PAROXYSMAL ATRIAL FIBRILLATION

Abhishek Bose, Parag Anilkumar Chevli, Zeba Hashmath, Ajay K. Mishra, Gregory Berberian, Jerzy Januszkiewicz and Ghasan Ahmad
Journal of the American College of Cardiology, Vol.77(18 Supplement 1), pp.324-324
05/11/2021
DOI: 10.1016/S0735-1097(21)01683-1

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Abstract

Background Cryoballoon ablation (CBA) is recommended for patients with paroxysmal atrial fibrillation (AF) refractory to anti-arrhythmic drugs. However, only 80% of patients benefit from an initial CBA. Smoking is known to be associated with an increased risk of development of AF, though its role in contributing to recurrence of atrial arrhythmias (AA) following CBA for paroxysmal AF is unclear. Methods We followed 103 patients (Age 60.6 ± 9.1, 29% women) with paroxysmal AF undergoing CBA for one year post procedure for development of atrial arrhythmias (AA). Recurrence was assessed by documented AA on EKG or any form of long term cardiac rhythm monitoring. Current smoking status as a predictor of recurrence was assessed in a multivariate cox proportional hazard model. Results After a one year follow up, 19 (18.4%) participants developed recurrence of AA. Patients were divided into three groups based on their current status: non-smoker, former smoker and current smoker. Baseline demographics were similar between the groups except for former smokers being older with a higher CHA2DS2-VASc score. On a multivariate model adjusted for baseline demographics and risk factors for AF, smoking status did not predict recurrence of AA following CBA (Table, p=0.82). Furthermore, on Kaplan-Meier analysis smoking status did not predict time to first recurrence of AA (Figure, p=0.75). Conclusion In patients with paroxysmal AF, current smoking status was not predictive of recurrence of AA following CBA.

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