Abstract
Timing of Cranial Vault Reconstruction in Non-Syndromic Craniosynostosis: A Single Institution’s 30-Year Experience
Journal of the American College of Surgeons, Vol.223(4), pp.S103-S104
10/2016
DOI: 10.1016/j.jamcollsurg.2016.06.213
Abstract
Introduction
Due to the changing properties of the infant skull, there is still no clear consensus on the ideal time to surgically intervene in cases of non-syndromic craniosynostosis (NSC). This study aimed to shed light on how age at time of operation may affect surgical outcomes and the subsequent need for reoperation.
Methods
A retrospective cohort review was conducted for patients with NSC who underwent primary cranial vault remodeling from 1990-2013. Patient demographics, characteristics, and surgical interventions were recorded. Postoperative outcomes were assessed by assigning each procedure to a Whitaker category. Multivariate logistic regression analysis was performed to determine the relationship between age at surgery and need for minor (Whitaker I/II) vs major (Whitaker III/IV) reoperation. Odds ratios (OR) for Whitaker category by age at surgery were assigned.
Results
A total of 413 unique patients underwent cranial vault remodeling procedures for NSC during the study period. Multivariate logistic regression demonstrated increased odds of requiring major surgical revisions (Whitaker III/IV) in patients < 6 months of age (OR 2.49, 95% CI 1.05-5.93), and increased odds of requiring minimal surgical revisions (Whitaker I/II) in patients > 6 months of age (OR 2.72, 95% CI 1.16-6.41).
Conclusions
Timing, as a proxy for the changing properties of the infant skull, is an important factor to consider when planning vault reconstruction in NSC. Our data demonstrate that patients operated on before 6 months of age had an increased odds ratio of requiring major surgical revisions.
Details
- Title: Subtitle
- Timing of Cranial Vault Reconstruction in Non-Syndromic Craniosynostosis: A Single Institution’s 30-Year Experience
- Creators
- Joseph Lopez - Johns Hopkins HospitalAlan F. Utria - Johns Hopkins HospitalRegina S. Cho - Johns Hopkins HospitalGerhard S. Mundinger - Johns Hopkins HospitalGeorge I. Jallo - Johns Hopkins HospitalEdward S. Ahn - Johns Hopkins HospitalCraig A. Vander KolkAmir H. Dorafshar - Johns Hopkins Hospital
- Resource Type
- Abstract
- Publication Details
- Journal of the American College of Surgeons, Vol.223(4), pp.S103-S104
- DOI
- 10.1016/j.jamcollsurg.2016.06.213
- ISSN
- 1072-7515
- eISSN
- 1879-1190
- Publisher
- ELSEVIER SCIENCE INC
- Language
- English
- Date published
- 10/2016
- Academic Unit
- Surgery
- Record Identifier
- 9985019946502771
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