Unnatural Amino Acid Mutagenesis Reveals the Critical Role of Hydrogen Bonding for Binding of Retigabine in the Pore of KCNQ Channels

Abstract

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Stephan A Pless, Michael Yau, Jason D Galpin, Christopher A Ahern and Harley T Kurata

Biophysical journal, Vol.106(2), pp.143a-143a

01/28/2014

DOI: 10.1016/j.bpj.2013.11.828

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Title: Subtitle: Unnatural Amino Acid Mutagenesis Reveals the Critical Role of Hydrogen Bonding for Binding of Retigabine in the Pore of KCNQ Channels
Creators: Stephan A Pless - University of British Columbia, Vancouver, BC, Canada
Michael Yau - University of British Columbia, Vancouver, BC, Canada
Jason D Galpin - University of Iowa, Iowa City, IA, USA
Christopher A Ahern - University of Iowa, Iowa City, IA, USA
Harley T Kurata - University of British Columbia, Vancouver, BC, Canada
Resource Type: Abstract
Publication Details: Biophysical journal, Vol.106(2), pp.143a-143a
Publisher: Elsevier Inc
DOI: 10.1016/j.bpj.2013.11.828
ISSN: 0006-3495
eISSN: 1542-0086
Language: English
Date published: 01/28/2014
Academic Unit: Molecular Physiology and Biophysics; Iowa Neuroscience Institute
Record Identifier: 9984071651202771

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