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Wnt signaling in granulosa cell tumors of the ovary
Abstract   Open access  Peer reviewed

Wnt signaling in granulosa cell tumors of the ovary

Brian M Kilonzo, Traci Neff, Megan I Samuelson and Michael J Goodheart
Proceedings in obstetrics and gynecology, Vol.4(3), pp.1-1
02/23/2015
DOI: 10.17077/2154-4751.1270
url
https://doi.org/10.17077/2154-4751.1270View
Published (Version of record) Open Access

Abstract

Granulosa cell tumors (GCT), a malignant type of sex-cord stromal tumor, account for approximately 2-5% of all ovarian malignancies. They are often identified before they have spread beyond the ovary, but advanced disease can be quite challenging to treat. Wnt signaling has been suggested to contribute to the formation of GCT. We hypothesized Wnt signaling was involved in human GCT.

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