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114 - Lymphomas presenting in the head and neck
Book chapter

114 - Lymphomas presenting in the head and neck

M. Junaid Hussain, Ricardo Cossyleon and Krishna Rao
Cummings Otolaryngology, pp.1785-1799.e5
Elsevier Health, Eighth Edition
2026
DOI: 10.1016/B978-0-443-11984-2.00123-7

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Abstract

Lymphomas are malignant neoplasms of lymphocytes and their precursor cells that are classified according to their morphologic, immunophenotypic, genetic, and clinical characteristics and not based solely on the anatomic location of tumor cells. Therefore, Otolaryngologists play a critical role in obtaining adequate tissue for accurate lymphoma classification. Additionally, lymphomas commonly occur initially in the head and neck, either as cervical or supraclavicular adenopathy or as a primary extranodal lymphoma of the thyroid, salivary gland, paranasal sinus, nasal cavity, or Waldeyer’s ring. Hence, lymphoma should be included in the differential diagnosis of any patient with adenopathy, salivary gland enlargement, or a mass in these regions. Since most lymphomas are highly treatable and are often curable, it is paramount to identify and categorize them. Here, we present an overview of the epidemiology, types, clinical presentation, diagnosis and current treatment options for lymphomas occurring in the head and neck.
CAR-T Head and Neck Hodgkin Lymphoma Non-Hodgkin

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