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6 - Abnormal puberty
Book chapter

6 - Abnormal puberty

Ellen Lancon Connor and Lauren A. Kanner
NASPAG's Principles & Practice of Pediatric and Adolescent Gynecology, pp.47-58
Elsevier Inc
2024
DOI: 10.1016/B978-0-443-10512-8.00015-1

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Abstract

Abnormal pubertal processes in the child may be classified as causing precocious or delayed puberty. Precocity should be evaluated to determine whether timing, tempo, or both are affected. Central precocity refers to early or rapid onset of hypothalamic and brain-driven pubertal changes, whereas peripheral sexual precocity refers to pubertal changes from elevation of sex steroids that are not directed by the hypothalamus and pituitary. Delayed puberty can be classified as abnormalities arising from congenital anatomic abnormalities, from the brain, from chronic disease, or from the gonads.
Delayed puberty hypergonadotropic hypogonadism hypogonadotropic hypogonadism Kallmann syndrome McCune-Albright syndrome MKRN3 precocious puberty premature menarche Turner syndrome

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