Book chapter
87Model Organisms of Cystic Fibrosis
Hodson and Geddes' Cystic Fibrosis, pp.87-95
CRC Press, Fifth Edition
2024
DOI: 10.1201/9781003262763-9
Abstract
Models of CF have been developed in multiple organisms over the last 30 years to assist with our understanding of disease pathophysiology. Ranging from fruit flies and zebrafish to mice, rats, ferrets, rabbits, pigs, and sheep, our knowledge of CF has been greatly enhanced by these models. Each CF model is unique, sharing variable amounts of similarity to the human disease, and each one provides distinct advantages for CF research. Selecting the right model of CF is dependent on the features of the model and the question being asked. This chapter reviews current models of CF and provides a guide for selecting a model based on characteristics and phenotypes.
Details
- Title: Subtitle
- 87Model Organisms of Cystic Fibrosis
- Creators
- Daniel P. CookDavid A. Stoltz
- Contributors
- Andrew Bush (Editor)Margarida D. Amaral (Editor)Jane C. Davies (Editor)Nicholas J. Simmonds (Editor)Jennifer L. Taylor-Cousar (Editor)Sarath Ranganathan (Editor)
- Resource Type
- Book chapter
- Publication Details
- Hodson and Geddes' Cystic Fibrosis, pp.87-95
- Edition
- Fifth Edition
- Publisher
- CRC Press
- DOI
- 10.1201/9781003262763-9
- Alternative title
- Model Organisms of Cystic Fibrosis
- Language
- English
- Date published
- 2024
- Academic Unit
- Molecular Physiology and Biophysics; Internal Medicine; Pulmonary, Critical Care, and Occupational Medicine
- Record Identifier
- 9984473933802771
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