Book chapter
A Short Synthesis of Strychnine from Pyridine
Total Synthesis of Natural Products, pp.67-102
Springer Berlin Heidelberg
11/15/2012
DOI: 10.1007/978-3-642-34065-9_4
Abstract
The synthesis of complex natural products serves as a source of great inspiration and challenge for organic chemists. The synthesis of strychnine is no exception. With six contiguous stereocenters, five of which adorn the central cyclohexane ring, a stereodefined trisubstituted olefin, and seven rings, strychnine (1, Fig. 4.1) presents a significant challenge for synthesis.
Details
- Title: Subtitle
- A Short Synthesis of Strychnine from Pyridine
- Creators
- David B. C Martin - Department of Chemistry, University of California, Irvine, USAChristopher D Vanderwal - Department of Chemistry, University of California, Irvine, USA
- Resource Type
- Book chapter
- Publication Details
- Total Synthesis of Natural Products, pp.67-102
- DOI
- 10.1007/978-3-642-34065-9_4
- Publisher
- Springer Berlin Heidelberg; Berlin, Heidelberg
- Language
- English
- Date published
- 11/15/2012
- Academic Unit
- Iowa Neuroscience Institute; Chemistry
- Record Identifier
- 9984065856002771
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