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Active Surveillance: The United States Food and Drug Administration's Sentinel Initiative
Book chapter

Active Surveillance: The United States Food and Drug Administration's Sentinel Initiative

Ryan M Carnahan, Carlos J Bell and Richard Platt
Mann's Pharmacovigilance, pp.429-437
John Wiley & Sons, Ltd
04/01/2014
DOI: 10.1002/9781118820186.ch27

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Abstract

The Sentinel Initiative is the active surveillance component of the postmarket safety surveillance system of the Food and Drug Administration (FDA). Mini‐Sentinel is a pilot program building the foundation for the Sentinel System. It is a collaboration between the FDA, academic institutions, and data partners that uses a distributed data system to allow analysis of data from health plans and other sources across a network of participating sites. This chapter provides an overview of the Sentinel Initiative, with a focus on Mini‐Sentinel.
active surveillance administrative data adverse effects claims data distributed data drug safety Food and Drug Administration Mini‐Sentinel Sentinel surveillance

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