Book chapter
Antibiotics for Preterm Premature Rupture of Membranes
50 Studies Every Obstetrician-Gynecologist Should Know, pp.43-47
50 studies every doctor should know, Oxford University Press
2021
DOI: 10.1093/med/9780190947088.003.0008
Abstract
Antibiotics for preterm prelabor rupture of membranes (PPROM) have been shown to prolong the length of pregnancy as well as improve neonatal outcomes as demonstrated by the landmark article by Mercer et al. PPROM complicates 3% of all pregnancies, and approximately onehalf of patients will deliver within 1 week of membrane rupture. Infection is thought to play a role in both the etiology of PPROM and subsequent maternal and neonatal complications. Premature birth further complicates neonatal outcomes, therefore prolongation of pregnancy after PPROM is essential for risk reduction. Administration of broad spectrum antibiotics have been associated with prolonged latency in women with PPROM at less than 32 weeks and 0 days of gestation as well as improved neonatal outcomes.
Details
- Title: Subtitle
- Antibiotics for Preterm Premature Rupture of Membranes
- Creators
- Katherine S. KohariChristian M. Pettker
- Resource Type
- Book chapter
- Publication Details
- 50 Studies Every Obstetrician-Gynecologist Should Know, pp.43-47
- Series
- 50 studies every doctor should know
- DOI
- 10.1093/med/9780190947088.003.0008
- Publisher
- Oxford University Press; New York, NY
- Language
- English
- Date published
- 2021
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9985244535502771
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