Book chapter
B Cell-Mediated Regulation of Immunity During Leishmania Infection
Control of Innate and Adaptive Immune Responses during Infectious Diseases, pp.85-98
Springer New York
08/25/2011
DOI: 10.1007/978-1-4614-0484-2_5
Abstract
Intracellular pathogens cause a wide spectrum of clinical disease ranging from mild self-limiting infections to chronic diseases and even acute life-threatening illnesses. T cell-mediated immunity is central to effective immune control of Leishmania infection and the role that B cells and antibodies play in promoting immunopathology during disease associated with chronic Leishmania infection is becoming more clear. However, the role that B cells and antibodies play during a successful immune response may be subtle and range from protecting the host from a robust cell-mediated response to enhancing immune effectiveness. The B cell response may therefore be a significant component of both ineffective and effective immunity to Leishmania infection.
Details
- Title: Subtitle
- B Cell-Mediated Regulation of Immunity During Leishmania Infection
- Creators
- Katherine N Gibson-CorleyChristine A PetersenDouglas E Jones - Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, USA
- Resource Type
- Book chapter
- Publication Details
- Control of Innate and Adaptive Immune Responses during Infectious Diseases, pp.85-98
- DOI
- 10.1007/978-1-4614-0484-2_5
- Publisher
- Springer New York; New York, NY
- Language
- English
- Date published
- 08/25/2011
- Academic Unit
- Epidemiology; Internal Medicine; Ophthalmology and Visual Sciences
- Record Identifier
- 9984214799902771
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