Book chapter
Basic Mechanisms of Voltage Sensing
Handbook of Ion Channels, pp.45-60
CRC Press
2015
DOI: 10.1201/b18027-9
Abstract
Since the early pioneering studies by Bernstein, Cole,
Hodgkin, Huxley, and others, voltage-sensitive conductances
have been extensively studied because of their primary role in
electrical excitability in nerves and muscles (2-11). Voltagedependent K+, Na+, and Ca++ channels are responsible for
generation of an action potential, which is the elementary unit
of electrical signals in biology. Calcium inux through calcium
channels can also act as a second messenger, which initiates
various processes such as muscle contraction (12,13). Isoforms
of voltage-dependent potassium channels are involved in diverse
physiological processes, which include volume regulation,
secretion, proliferation, and migration.
Details
- Title: Subtitle
- Basic Mechanisms of Voltage Sensing
- Creators
- Sandipan Chowdhury - University of Iowa, Molecular Physiology and BiophysicsBaron Chanda
- Contributors
- Jie Zheng (Editor)Matthew C Trudeau (Editor)
- Resource Type
- Book chapter
- Publication Details
- Handbook of Ion Channels, pp.45-60
- DOI
- 10.1201/b18027-9
- Publisher
- CRC Press
- Language
- English
- Date published
- 2015
- Academic Unit
- Molecular Physiology and Biophysics
- Record Identifier
- 9984297500402771
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