Book chapter
Biomechanics of Keratoconus
Keratoconus, pp.23-29
Springer Nature Singapore
10/20/2022
DOI: 10.1007/978-981-19-4262-4_3
Abstract
Keratoconus (KCN) is a bilateral ectasia marked by progressive thinning and protrusion at the apex. This conical protrusion is secondary to molecular changes resulting in structural instability and biomechanical changes. Keratoconic corneas demonstrate more pliability in their biomechanical parameters, such as increased hysteresis and increased deformation amplitude. Algorithms combining biomechanical parameters with topographic markers enable clinicians to identify and treat KCN and forme fruste KCN (ffKCN) prior to the onset of vision-compromising irregular astigmatism and apical scarring. Monitoring the biomechanical changes to the properties of corneas after treatment demonstrates therapeutic effect and stability. The Ocular Response Analyzer and Corvis ST devices are the predominant in vivo biomechanical biometers currently in use, but multiple technologies are in development.
Details
- Title: Subtitle
- Biomechanics of Keratoconus
- Creators
- Kanwal Singh Matharu - University of PittsburghJiaonan MaYan Wang - Tianjin Medical UniversityVishal Jhanji - University of Pittsburgh
- Resource Type
- Book chapter
- Publication Details
- Keratoconus, pp.23-29
- Publisher
- Springer Nature Singapore; Singapore
- DOI
- 10.1007/978-981-19-4262-4_3
- Language
- English
- Date published
- 10/20/2022
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984459627602771
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