Book chapter
Carcinoid Crisis
Endocrine Surgery Comprehensive Board Exam Guide, pp.1039-1052
Springer International Publishing
01/19/2022
DOI: 10.1007/978-3-030-84737-1_43
Abstract
Neuroendocrine tumors (NETs) can produce multiple hormones of which 5-hydroxytryptamine (serotonin) is the most recognized. Carcinoid syndrome (CS) may develop in patients with hormone-producing NETs when systemic hormone levels are elevated. The overproduction of hormones leads to CS symptoms and stimulates fibrosis, which can cause carcinoid-associated complications such as mesenteric fibrosis and carcinoid heart disease, and patients may develop anxiety, depression, and cognitive impairment. Management of CS focuses on reducing serotonin levels with somatostatin analogs (SSAs). Carcinoid crisis is a potentially life-threatening complication in patients with hormone-producing NETs, and this chapter reviews consideration for management of such patients.
Details
- Title: Subtitle
- Carcinoid Crisis
- Creators
- Alexandra Gangi - Cedars-Sinai Medical CenterJames R. Howe - University of Iowa Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, USA
- Resource Type
- Book chapter
- Publication Details
- Endocrine Surgery Comprehensive Board Exam Guide, pp.1039-1052
- Publisher
- Springer International Publishing; Cham
- DOI
- 10.1007/978-3-030-84737-1_43
- Language
- English
- Date published
- 01/19/2022
- Academic Unit
- Surgery
- Record Identifier
- 9984322772202771
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