Book chapter
Central Nervous System Vasculitis - 24
Springer International Publishing
01/01/2021
Abstract
Central nervous system (CNS) vasculitis may occur in isolation (primary angiitis of the CNS or PACNS) or in the setting of systemic vasculitis, connective tissue disease, infection, or other miscellaneous conditions (secondary CNS vasculitis). PACNS remains a diagnostic challenge for physicians, owing to protean clinical manifestations and lack of specific diagnostic tests for PACNS. Evaluation of suspected PACNS must therefore be focused on excluding causes of secondary CNS vasculitis and non-vasculitic conditions mimicking PACNS. Treatment of PACNS involves long-term immunosuppression. Most show a favorable response to treatment; however, relapses are not uncommon. Historically, PACNS was felt to be universally fatal, but increased awareness and advances in diagnostic testing have seen a decrease in mortality from PACNS in more recent years. Physicians must maintain a high level of clinical suspicion in order to promptly detect and evaluate cases of possible CNS vasculitis, as delays in diagnosis and treatment may result in significant morbidity and mortality.
Details
- Title: Subtitle
- Central Nervous System Vasculitis - 24
- Creators
- Christine M GillAmanda L PiquetTracey A Cho
- Resource Type
- Book chapter
- Publisher
- Springer International Publishing
- Language
- English
- Date published
- 01/01/2021
- Academic Unit
- Neurology; Iowa Neuroscience Institute
- Record Identifier
- 9984083947602771
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